Gene structure and chromosome mapping of the human small-conductance calcium-activated potassium channel SK1 gene (KCNN1)

被引：13

作者：

Litt, M ^{[1
]}

LaMorticella, D

Bond, CT

Adelman, JP

机构：

[1] Oregon Hlth Sci Univ, Dept Mol & Med Genet, Portland, OR 97201 USA

[2] Oregon Hlth Sci Univ, Vollum Inst, Portland, OR 97201 USA

来源：

CYTOGENETICS AND CELL GENETICS | 1999年 / 86卷 / 01期

关键词：

D O I：

10.1159/000015415

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Small-conductance, calcium-activated potassium channels contribute to the afterhyperpolarization in central neurons and other cell types. Because these channels regulate neuronal excitability, defects in their genes could cause excitability disorders. The human cDNA encoding one such channel, SK1 (KCNN1), was recently cloned. Here we describe the gene structure of KCNN1 and its localization by radiation hybrid mapping to chromosome 19p13.1.

引用

页码：70 / 73

页数：4

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