In vivo measurement of mid-infrared light scattering from human skin

被引:35
作者
Michel, Anna P. M. [1 ]
Liakat, Sabbir [2 ]
Bors, Kevin [2 ]
Gmachl, Claire F. [1 ,2 ]
机构
[1] Princeton Univ, Princeton Inst Sci & Technol Mat, Princeton, NJ 08540 USA
[2] Princeton Univ, Dept Elect Engn, Princeton, NJ 08540 USA
来源
BIOMEDICAL OPTICS EXPRESS | 2013年 / 4卷 / 04期
关键词
MECHANISMS; TISSUE;
D O I
10.1364/BOE.4.000520
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Two mid-infrared light sources, a broadband source from a Fourier Transform Infrared Spectrometer (FTIR) and a pulsed Quantum Cascade (QC) Laser, are used to measure angle-resolved backscattering in vivo from human skin across a broad spectral range. Scattering profiles measured using the FTIR suggest limited penetration of the light into the skin, with most of the light interacting with the stratum corneum layer of the epidermis. Scattering profiles from the QC laser show modulation patterns with angle suggesting interaction with scattering centers in the skin. The scattering is attributed to interaction of the laser light with components such as collagen fibers and capillaries in the dermis layer of the skin. (C) 2013 Optical Society of America
引用
收藏
页码:520 / 530
页数:11
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