Efficient synthesis and insecticidal activity of novel pyridin-3-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles

被引：0

作者：

Qian, Qun ^{[1
]}

Zhu, Yiwen ^{[1
]}

Zhang, Min ^{[1
]}

Lu, Dongliang ^{[1
]}

Cao, Weiguo ^{[2
]}

Song, Liping ^{[2
]}

Huang, Qingchun ^{[3
]}

机构：

[1] Shanghai Univ, Coll Sci, Dept Chem, Shanghai 200444, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China

[3] E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

来源：

MONATSHEFTE FUR CHEMIE | 2013年 / 144卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Pyridine; 1,2,4]Triazolo[3,4-b][1,3,4]thiadiazoles; Bioactivity; DERIVATIVES; TRIAZOLE;

D O I：

10.1007/s00706-012-0798-1

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of novel [1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles bearing pyridine ring derivatives was synthesized from 2,6-dimethylpyridin-3,5-dicarboxylic acid diethyl ester. The structures of the compounds were characterized by use of IR, NMR, EI-MS, and elemental analysis. The structure of one compound was further confirmed by X-ray diffraction analysis. Biological assays showed that these compounds had potential insecticidal activity with especially strong regulation of the growth of 2nd instar Mythimna separata larvae. The effects on bioactivity of substituent groups on phenyl ring were also screened. .

引用

页码：231 / 236

页数：6

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