Repetitive transcranial magnetic stimulation in anorexia nervosa: A pilot study

被引：64

作者：

Van den Eynde, F. ^{[1
]}

Guillaume, S. ^{[1
,2
]}

Broadbent, H. ^{[1
]}

Campbell, I. C. ^{[1
]}

Schmidt, U. ^{[1
]}

机构：

[1] Kings Coll London, Inst Psychiat, Sect Eating Disorders, London SE5 8AF, England

[2] Univ Montpellier I, CHU Montpellier, INSERM, U1061, F-34006 Montpellier, France

来源：

EUROPEAN PSYCHIATRY | 2013年 / 28卷 / 02期

关键词：

Anorexia nervosa; Repetitive transcranial magnetic stimulation; Eating disorders; Dorsolateral prefrontal cortex Interoceptive awareness; Cortisol concentrations; EATING-DISORDERS; DEPRESSION; SAFETY;

D O I：

10.1016/j.eurpsy.2011.06.002

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

The search for new treatments to improve outcome in people with anorexia nervosa continues. This pilot study investigated whether one session of high frequency repetitive transcranial magnetic stimulation (rTMS) delivered to the left dorsolateral prefrontal cortex reduces eating disorder related symptoms following exposure to visual and real food stimuli. Safety and tolerability were also assessed. Ten right-handed people with anorexia nervosa underwent one session of rTMS. Subjective experiences related to the eating disorder (e.g. urge to restrict, feeling full etc.) were assessed before and after rTMS. Nonparametric repeated measures tests were used. rTMS was safe and well- tolerated, and resulted in reduced levels of feeling full, feeling fat and feeling anxious. Thus, rTMS may reduce core symptoms of anorexia nervosa. Future research should establish the therapeutic potential of rTMS in anorexia nervosa. (C) 2011 Elsevier Masson SAS. All rights reserved.

引用

页码：98 / 101

页数：4

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