Teaching Old Drugs New Tricks: Statins for COVID-19?

被引：29

作者：

Fajgenbaum, David C. ^{[1
,3
,4
]}

Rader, Daniel J. ^{[1
,2
,3
]}

机构：

[1] Univ Penn, Dept Med, Perelman Sch Med, Div Translat Med & Human Genet, Philadelphia, PA 19104 USA

[2] Univ Penn, Dept Genet, Perelman Sch Med, Philadelphia, PA 19104 USA

[3] Univ Penn, Perelman Sch Med, Inst Translat Med & Therapeut, Philadelphia, PA 19104 USA

[4] Univ Penn, Dept Med, Perelman Sch Med, Ctr Cytokine Storm Treatment & Lab, Philadelphia, PA 19104 USA

来源：

CELL METABOLISM | 2020年 / 32卷 / 02期

基金：

美国国家卫生研究院;

关键词：

FLUVASTATIN; EXPRESSION;

D O I：

10.1016/j.cmet.2020.07.006

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The COVID-19 pandemic has driven unprecedented efforts to identify existing treatments that can be quickly and effectively repurposed to reduce morbidity and mortality. In this issue of Cell Metabolism, Zhang et al. (2020) report an association between statin use and improved outcomes in a large observational study of hospitalized COVID-19 patients. Given the widespread availability, low cost, and safety of statins, this prom-ising result should be further investigated in randomized controlled trials.

引用

页码：145 / 147

页数：3

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