Synthetic approaches to natural products containing 2,3-dihydrobenzofuran skeleton

被引:100
作者
Chen, Zhuang [1 ]
Pitchakuntla, Mallesham [1 ]
Jia, Yanxing [1 ]
机构
[1] Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, 38 Xueyuan Rd, Beijing 100191, Peoples R China
基金
中国国家自然科学基金;
关键词
ENANTIOSELECTIVE TOTAL-SYNTHESIS; POTENT INHIBITORY-ACTIVITY; TRICYCLIC HEXAHYDRODIBENZOFURAN CONSTITUENT; HYPERVALENT IODINE OXIDATION; LINDERA-UMBELLATA BARK; ABSOLUTE-CONFIGURATION; LITHOSPERMUM-RUDERALE; MELANIN BIOSYNTHESIS; (+)-LITHOSPERMIC ACID; POLYPHENOLIC ACIDS;
D O I
10.1039/c8np00072g
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Natural products containing the 2,3-dihydrobenzofuran (2,3-DHB) skeleton have been the focus of a substantial number of synthetic studies since 2000. Herein, we review the total syntheses of decursivine, serotobenine, lithospermic acid, linderol A, bisabosqual A, pterocarpans, conocarpan, heliannuols, and some resveratrol oligomers, with emphasis on the synthetic strategies employed.
引用
收藏
页码:666 / 690
页数:25
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