Repetitive abortion in Neospora-infected ewes

被引:43
作者
Jolley, WR [1 ]
McAllister, MM [1 ]
McGuire, AM [1 ]
Wills, RA [1 ]
机构
[1] Univ Wyoming, Dept Vet Sci, Laramie, WY 82070 USA
关键词
Neospora caninum; ovine neosporosis; repetitive abortion;
D O I
10.1016/S0304-4017(99)00017-5
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Pregnant ewes inoculated with cultured Neospora caninum tachyzoites in 1995, 1996, or 1995 and 1996 aborted or delivered weak or clinically normal lambs in 1996. Nine of 11 ewes in the study had previously produced infected lambs or fetuses after being experimentally infected in 1995. Fetuses and lambs produced in 1996 showed histologic lesions and zoites indicative of Neospora. Serologic responses and production of infected fetuses/lambs indicated systemic neosporosis in the ewes during gestation, although tachyzoites could not be cultured from maternal tissues. The repetitive infection of fetuses, and resulting clinical and histopathologic findings in the present study are similar to those reported in naturally infected cattle, adding to the already established similarities of neosporosis between sheep and cattle. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:251 / 257
页数:7
相关论文
共 13 条
[1]   Characterization of the first European isolate of Neospora caninum (Dubey, Carpenter, Speer, Topper and Uggla) [J].
Barber, JS ;
Holmdahl, OJM ;
Owen, MR ;
Guy, F ;
Uggla, A ;
Trees, AJ .
PARASITOLOGY, 1995, 111 :563-568
[2]  
BARR BC, 1993, J AM VET MED ASSOC, V202, P113
[3]   Experimental infection of non-pregnant and pregnant sheep with Neospora caninum [J].
Buxton, D ;
Maley, SW ;
Thomson, KM ;
Trees, AJ ;
Innes, EA .
JOURNAL OF COMPARATIVE PATHOLOGY, 1997, 117 (01) :1-16
[4]   DETECTION OF NEOSPORA-CANINUM IN TISSUE-SECTIONS USING A MURINE MONOCLONAL-ANTIBODY [J].
COLE, RA ;
LINDSAY, DS ;
DUBEY, JP ;
BLAGBURN, BL .
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 1993, 5 (04) :579-584
[5]   A review of Neospora caninum and neosporosis [J].
Dubey, JP ;
Lindsay, DS .
VETERINARY PARASITOLOGY, 1996, 67 (1-2) :1-59
[6]  
Dubey JP, 1996, AM J VET RES, V57, P329
[7]   TOXOPLASMA-GONDII IN IOWA SOWS - COMPARISON OF ANTIBODY-TITERS TO ISOLATION OF TOXOPLASMA-GONDII BY BIOASSAYS IN MICE AND CATS [J].
DUBEY, JP ;
THULLIEZ, P ;
POWELL, EC .
JOURNAL OF PARASITOLOGY, 1995, 81 (01) :48-53
[8]  
GOU ZG, 1995, PARASITOL RES, V81, P365
[9]  
HAY WH, 1990, J AM VET MED ASSOC, V197, P87
[10]   Experimental neosporosis in pregnant ewes and their offspring [J].
McAllister, MM ;
McGuire, AM ;
Jolley, WR ;
Lindsay, DS ;
Trees, AJ ;
Stobart, RH .
VETERINARY PATHOLOGY, 1996, 33 (06) :647-655