Antimicrobial therapy of febrile complications after high-dose chemotherapy and autologous hematopoietic stem cell transplantation-guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)

被引：26

作者：

Weissinger, Florian ^{[1
]}

Auner, Holger W. ^{[2
]}

Bertz, Hartmut ^{[3
]}

Buchheidt, Dieter ^{[4
]}

Cornely, Oliver A. ^{[5
,6
]}

Egerer, Gerlinde ^{[7
]}

Heinz, Werner ^{[8
]}

Karthaus, Meinolf ^{[9
]}

Kiehl, Michael ^{[10
]}

Krueger, William ^{[11
]}

Penack, Olaf ^{[12
]}

Reuter, Stefan ^{[13
]}

Ruhnke, Markus ^{[14
]}

Sandherr, Michael

Salwender, Hans-Juergen ^{[15
]}

Ullmann, Andrew J. ^{[16
]}

Waldschmidt, Dirk T. ^{[17
]}

Wolf, Hans H. ^{[18
]}

机构：

[1] Evangel Krankenhaus Bielefeld, Klin Innere Med Hamatol Onkol & Palliat Med, D-33611 Bielefeld, Germany

[2] Univ London Imperial Coll Sci Technol & Med, Hammersmith Hosp, Dept Haematol, London, England

[3] Univ Klinikum Freiburg, Innere Med Abt 1, Freiburg, Germany

[4] Univ Klinikum Mannheim, Innere Med Klin 3, Mannheim, Germany

[5] Univ Cologne, Innere Med Klin 1, D-50931 Cologne, Germany

[6] Univ Cologne, Zentrum Klin Studien, D-50931 Cologne, Germany

[7] Univ Klinikum Heidelberg, Med Klin 5, Heidelberg, Germany

[8] Univ Wurzburg, Med Klin & Poliklin 2, D-97080 Wurzburg, Germany

[9] Klinikum Neuperlach, Klin Hamatol & Onkol, Munich, Germany

[10] Klinikum Frankfurt Oder, Med Klin 1, Frankfurt, Oder, Germany

[11] Univ Greifswald, Klin & Poliklin Innere Med C, Greifswald, Germany

[12] Charite, Abt Onkol & Hamatol, D-13353 Berlin, Germany

[13] Klinikum Leverkusen, Med Klin 4, Leverkusen, Germany

[14] Charite, Med Klin & Poliklin 2, D-13353 Berlin, Germany

[15] Asklepios Klin Altona, Med Abt 2, Hamburg, Germany

[16] Johannes Gutenberg Univ Mainz, Med Abt 3, Mainz, Germany

[17] Univ Cologne, Innere Med Klin 1, D-50931 Cologne, Germany

[18] Univ Halle Wittenberg, Halle, Germany

来源：

ANNALS OF HEMATOLOGY | 2012年 / 91卷 / 08期

关键词：

Autologous stem cell transplantation; Diagnostics for infection; Anti-infective therapy; Prophylaxis of infection; Supportive therapy for auto-SCT; BONE-MARROW-TRANSPLANTATION; NEUTROPENIC CANCER-PATIENTS; INVASIVE FUNGAL-INFECTIONS; BLOOD-STREAM INFECTION; B-VIRUS REACTIVATION; INTENSIVE-CARE-UNIT; RISK-FACTORS; CIRCULATING GALACTOMANNAN; CLOSTRIDIUM-DIFFICILE; BACTERIAL-INFECTION;

D O I：

10.1007/s00277-012-1456-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

More than 18,000 autolgous transplantation were performed in Europe in the year 2009. It as a routine procedure in experienced centres. Even if there is a low mortality rate, infections are a major issue after transplantation, occurring in more than 60 % of the patients. In this review we discuss all aspects of infections after autologous stem transplantation, including epidemiology, diagnostics, therapeutic algorithms, prophylaxis and supportive therapy.

引用

页码：1161 / 1174

页数：14

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