A scoping review of cost-effectiveness of screening and treatment for latent tubercolosis infection in migrants from high-incidence countries

被引：48

作者：

Zammarchi, Lorenzo ^{[1
]}

Casadei, Gianluigi ^{[2
]}

Strohmeyer, Marianne ^{[1
]}

Bartalesi, Filippo ^{[3
]}

Liendo, Carola ^{[4
]}

Matteelli, Alberto ^{[5
]}

Bonati, Maurizio ^{[2
]}

Gotuzzo, Eduardo ^{[4
]}

Bartoloni, Alessandro ^{[1
,3
]}

机构：

[1] Univ Florence, Sch Med, Dept Expt & Clin Med, Infect Dis Unit, I-50134 Florence, Italy

[2] Ist Ric Farmacol Mario Negri, IRCCS, Dept Publ Hlth, Lab Mother & Child Hlth, I-20156 Milan, Italy

[3] Azienda Osped Univ Careggi, SOD Malattie Infett & Trop, I-50134 Florence, Italy

[4] Univ Peruana Cayetano Heredia, Inst Med Trop Alexander von Humboldt, Lima, Peru

[5] Univ Brescia, Inst Infect & Trop Diaseases, WHO Collaborting Ctr TB Coinfect & TB Eliminat, Brescia, Italy

来源：

BMC HEALTH SERVICES RESEARCH | 2015年 / 15卷

基金：

欧盟第七框架计划;

关键词：

FOREIGN-BORN POPULATIONS; GAMMA RELEASE ASSAYS; TUBERCULOSIS INFECTION; UNITED-STATES; IMMIGRANTS; TRANSMISSION; PREVALENCE; CONTACT; HEALTH; TB;

D O I：

10.1186/s12913-015-1045-3

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Background: In low-incidence countries, most tuberculosis (TB) cases occur among migrants and are caused by reactivation of latent tuberculosis infection (LTBI) acquired in the country of origin. Diagnosis and treatment of LTBI are rarely implemented to reduce the burden of TB in immigrants, partly because the cost-effectiveness profile of this intervention is uncertain. The objective of this research is to perform a review of the literature to assess the cost-effectiveness of LTBI diagnosis and treatment strategies in migrants. Methods: Scoping review of economic evaluations on LTBI screening strategies for migrants was carried out in Medline. Results: Nine studies met the inclusion criteria. LTBI screening was cost-effective according to seven studies. Findings of four studies support interferon gamma release assay as the most cost-effective test for LTBI screening in migrants. Two studies found that LTBI screening is cost-effective only if carried out in immigrants who are contacts of active TB cases. Discussion and Conclusions: Our findings support the cost-effectiveness of LTBI diagnostic and treatment strategies in migrants especially if they are focused on young subjects from high incidence countries. These strategies could represent and adjunctive and synergistic tool to achieve the ambitious aim of TB elimination.

引用

页数：11

共 35 条

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