Utility of Doppler sonography for renal artery stenosis screening in obese children with hypertension

被引:6
作者
Makhija, Pooja [1 ]
Wilson, Christopher [2 ]
Garimella, Sudha [3 ]
机构
[1] SUNY Buffalo, Sch Med & Biomed Sci, Dept Pediat, Buffalo, NY USA
[2] Clemson Univ, Dept Math Sci, Coll Engn & Sci, Clemson, SC USA
[3] Univ South Carolina, Greenville Hlth Syst, Sch Med, Greenville, SC 29208 USA
关键词
Doppler; hypertension; obesity; pediatrics; vascular disease; RESISTIVE INDEX; BLOOD-PRESSURE; ULTRASOUND; KIDNEY; MECHANISMS; FAILURE; PREDICT;
D O I
10.1111/jch.13241
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Pediatric hypertension guidelines recommend Doppler renal ultrasonography as a screening study for the evaluation of possible renal artery stenosis (RAS) in normal-weight children 8years of age who are suspected of having RAS and who will cooperate with the procedure. Obese children are excluded because of technical and vascular concerns. There are no data on RI in obese children. This is a retrospective review of children aged 1.5-18 who received Doppler imaging studies over a 10-year period. A total of 174 patients were studied. There was no significant difference between the RI values based on BMI. Of the 174 individuals in the study 22 obtained follow-up CT/MRA after abnormal Doppler ultrasounds. On advanced imaging 3 were confirmed to have RAS. Obesity does not seem to influence RI.RI alone should not be used as a screening tool for RAS. An approach toward diagnosis is suggested based on BMI, renin levels, and ultrasound.
引用
收藏
页码:807 / 813
页数:7
相关论文
共 32 条
[1]  
[Anonymous], CHILD TEEN BMI
[2]   Ability of blood pressure to predict left ventricular hypertrophy in children with primary hypertension [J].
Brady, Tammy M. ;
Fivush, Barbara ;
Flynn, Joseph T. ;
Parekh, Rulan .
JOURNAL OF PEDIATRICS, 2008, 152 (01) :73-78
[3]   Value of Doppler ultrasound for the diagnosis of renal artery stenosis in children [J].
Brun, P ;
Kchouk, H ;
Mouchet, B ;
Baudouin, V ;
Raynaud, A ;
Loirat, C ;
AzancotBenisty, A .
PEDIATRIC NEPHROLOGY, 1997, 11 (01) :27-30
[4]   AGE DEPENDENCY OF THE RENAL RESISTIVE INDEX IN HEALTHY-CHILDREN [J].
BUDE, RO ;
DIPIETRO, MA ;
PLATT, JF ;
RUBIN, JM ;
MIESOWICZ, S ;
LUNDQUIST, C .
RADIOLOGY, 1992, 184 (02) :469-473
[5]  
DEEG KH, 1990, MONATSSCHR KINDERH, V138, P337
[6]  
Flynn JT, 2017, PEDIATRICS, V140, DOI [10.1542/peds.2017-1904, 10.1542/peds.2017-3035]
[7]   RENAL AND CARDIOVASCULAR MECHANISMS OF HYPERTENSION IN OBESITY [J].
HALL, JE .
HYPERTENSION, 1994, 23 (03) :381-394
[8]   Obesity-induced Hypertension: Role of Sympathetic Nervous System, Leptin, and Melanocortins [J].
Hall, John E. ;
da Silva, Alexandre A. ;
do Carmo, Jussara M. ;
Dubinion, John ;
Hamza, Shereen ;
Munusamy, Shankar ;
Smith, Grant ;
Stec, David E. .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (23) :17271-17276
[9]   Obesity, hypertension, and chronic kidney disease [J].
Hall, Michael E. ;
do Carmo, Jussara M. ;
da Silva, Alexandre A. ;
Juncos, Luis A. ;
Wang, Zhen ;
Hall, John E. .
INTERNATIONAL JOURNAL OF NEPHROLOGY AND RENOVASCULAR DISEASE, 2014, 7 :75-88
[10]  
Henegar JR, 2001, J AM SOC NEPHROL, V12, P1211, DOI 10.1681/ASN.V1261211