Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin

被引：89

作者：

Jambhrunkar, Siddharth ^{[1
]}

Karmakar, Surajit ^{[1
]}

Popat, Amirali ^{[1
]}

Yu, Meihua ^{[1
]}

Yu, Chengzhong ^{[1
]}

机构：

[1] Univ Queensland, Australian Inst Bioengn & Nanotechnol, Brisbane, Qld 4072, Australia

来源：

RSC ADVANCES | 2014年 / 4卷 / 02期

基金：

澳大利亚研究理事会;

关键词：

DRUG-DELIVERY SYSTEM; IMPROVING BIOAVAILABILITY; CANCER-THERAPY; APOPTOSIS; MCM-41; BIOCOMPATIBILITY; DEGRADATION; EXPRESSION; STABILITY; RELEASE;

D O I：

10.1039/c3ra44257h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Curcumin encapsulated in mesoporous silica nanoparticles showed improved solubility, in vitro release profile and significantly enhanced cell cytotoxicity compared to the pure drug.

引用

页码：709 / 712

页数：4

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