Direct observation of non-covalent complexes for phosphorylated flavor noidprotein interaction by ESI

被引：0

作者：

Chen, XL ^{[1
]}

Zhang, T

Liu, HX

Qu, LB

Yu, YZ

Zhao, YF

机构：

[1] Zhengzhou Univ, Dept Chem, Zhengzhou 450052, Peoples R China

[2] Tsinghua Univ, Sch Life Sci, Dept Chem, Key Lab Bioorgan Phosphorus Chem, Beijing 100084, Peoples R China

来源：

CHINESE CHEMICAL LETTERS | 2004年 / 15卷 / 03期

关键词：

DEPH; 7-hydroxyflavone; phosphorylation; ESI-MS; myoglobin; hen egg white lysozyme (HEWL); bovine insulin; non-covalent complexes;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Diethyl flavon-7-yl phosphate was synthesized by modified Atheron-Todd reaction. The result of ESI shows that the phosphated flavonoids possess stronger binding affinities toward proteins such as myoglobin, insulin and lysozyme and are easier to form the non-covalent complexes with them.

引用

页码：343 / 346

页数：4

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