Diatom-Specific Oligosaccharide and Polysaccharide Structures Help to Unravel Biosynthetic Capabilities in Diatoms

被引:133
作者
Guegi, Bruno [1 ]
Le Costaouec, Tinaig [2 ]
Burel, Carole [1 ]
Lerouge, Patrice [1 ]
Helbert, William [2 ]
Bardor, Muriel [1 ,3 ]
机构
[1] Univ Rouen, Normandie Univ, Inst Rech & Innovat Biomed,Fac Sci & Tech, Vegetale Agron Sol Innovat,Lab Glyco MEV EA 4358, F-76821 Mont St Aignan, France
[2] Univ Grenoble Alpes, Ctr Rech Macromol Vegetales CERMAV, CNRS, CERMAV, F-38000 Grenoble, France
[3] Inst Univ France, F-75005 Paris, France
关键词
microalgae; glycan; polysaccharide; diatom; exopolysaccharides; EPS; nucleotide sugars; EXTRACELLULAR POLYMERIC SUBSTANCES; CHITIN FIBRIL FORMATION; SILICA SHELL FORMATION; MARINE DIATOMS; PHAEODACTYLUM-TRICORNUTUM; THALASSIOSIRA-FLUVIATILIS; N-GLYCOSYLATION; FINE-STRUCTURE; CYLINDROTHECA-CLOSTERIUM; SKELETONEMA-COSTATUM;
D O I
10.3390/md13095993
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Diatoms are marine organisms that represent one of the most important sources of biomass in the ocean, accounting for about 40% of marine primary production, and in the biosphere, contributing up to 20% of global CO2 fixation. There has been a recent surge in developing the use of diatoms as a source of bioactive compounds in the food and cosmetic industries. In addition, the potential of diatoms such as Phaeodactylum tricornutum as cell factories for the production of biopharmaceuticals is currently under evaluation. These biotechnological applications require a comprehensive understanding of the sugar biosynthesis pathways that operate in diatoms. Here, we review diatom glycan and polysaccharide structures, thus revealing their sugar biosynthesis capabilities.
引用
收藏
页码:5993 / 6018
页数:26
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