Pathophysiology I: the kidney and the sympathetic nervous system

被引：10

作者：

de Jager, Rosa L. ^{[1
]}

Blankestijn, Peter J. ^{[1
]}

机构：

[1] Univ Med Ctr Ufrecht, Dept Nephrol, NL-3508 GA Utrecht, Netherlands

来源：

EUROINTERVENTION | 2013年 / 9卷

关键词：

hypertension; pathophysiology; renal denervation; renin angiotensin system; sympathetic nervous system; CHRONIC-RENAL-FAILURE; RESISTANT HYPERTENSION; ANGIOTENSIN-II; DISEASE PATIENTS; BLOOD-PRESSURE; DENERVATION; HYPERACTIVITY; ACTIVATION; SPIRONOLACTONE; CHLORTHALIDONE;

D O I：

10.4244/EIJV9SRA8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Recently, catheter-based renal denervation (RDN) has become available. In order to understand better the possible role of RDN as a treatment modality, we first discuss the anatomy and function of the renal nerves in this brief review. Secondly, we address the question - what is the clinical evidence for the involvement of the kidneys and renal nerves in the pathogenesis of sympathetic hyperactivity. Finally, we will discuss how this sympathetic hyperactivity can be reduced, specifically addressing the possible role of RDN.

引用

页码：R42 / R47

页数：6

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