Association and expression analysis of porcine HNF1A gene related to meat and carcass quality traits

被引：8
作者：
Kayan, Autchara [1 ,2 ]
Uddin, Muhammad Jasim [1 ,3 ]
Kocamis, Hakan [4 ]
Tesfaye, Dawit [1 ]
Looft, Christian [1 ]
Tholen, Ernst [1 ]
Schellander, Karl [1 ]
Cinar, Mehmet Ulas [1 ]
机构：
[1] Univ Bonn, Inst Anim Sci, Anim Breeding & Husb Grp, D-53115 Bonn, Germany
[2] Kasetsart Univ, Fac Agr, Dapartment Anim Sci, Bangkok 10900, Thailand
[3] Bangladesh Agr Univ, Fac Vet Sci, Dept Med, Mymensingh 2202, Bangladesh
[4] Kirikkale Univ, Fac Vet, Dept Histol & Embryol, TR-71450 Kirikkale, Turkey
来源：
MEAT SCIENCE | 2013年 / 94卷 / 04期
关键词：
HNF1A; Single nucleotide polymorphism; mRNA and protein expression; Methylation; Meat quality; Pig; INTRAMUSCULAR FAT-CONTENT; ACID-COMPOSITION; DNA METHYLATION; QTL; IDENTIFICATION; HEPATOCYTE-NUCLEAR-FACTOR-1-ALPHA; POLYMORPHISMS; ACTIVATION; FATNESS; TARGET;
D O I：
10.1016/j.meatsci.2013.04.015
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
The aim of this study was to investigate the association and expression of HNF1A gene as a candidate gene for meat and carcass quality traits in pigs. Statistical analysis revealed that the g.8260 A>G polymorphism significantly associated with pH 24(H), meat percentage and muscle area in the F-2 Duroc x Pietrain (DuPi, n = 313) and with pH 24(L), fat area and backfat thickness in the Pietrain (Pi, n = 110) population. HNF1A mRNA and protein expressions were higher (p < 0.05) in animals with the low post-mortem muscle pH 24(L). The promoter methylation profiling suggested that methylation was not involved on HNF1A expression regulation (p > 0.05) in animal with divergent muscle pH. In conclusion, polymorphism in porcine HNF1A gene could be used as a candidate marker to improve the meat and carcass quality traits, with the consideration of breed-specific effect. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：474 / 479
页数：6
相关论文
共 50 条
  • [41] A genome-wide association analysis for carcass and meat quality traits in Duroc pigs
    Gonzalez, R.
    Eusebi, P. G.
    Quintanilla, R.
    Figueiredo, T.
    Manunza, A.
    Noguera, J. L.
    Clop, A.
    Amills, M.
    JOURNAL OF ANIMAL SCIENCE, 2016, 94 : 119 - 120
  • [42] Association of ADSL gene polymorphisms with meat quality and carcass traits in domestic pigeons (Columba livia)
    Mao, H. G.
    Cao, H. Y.
    Liu, H. H.
    Dong, X. Y.
    Xu, N. Y.
    Yin, Z. Z.
    BRITISH POULTRY SCIENCE, 2018, 59 (05) : 604 - 607
  • [43] SNP Discovery in the Leptin Promoter Gene and Association with Meat Quality and Carcass Traits in Korean Cattle
    Chung, E. R.
    Shin, S. C.
    Shin, K. H.
    Chung, K. Y.
    ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 2008, 21 (12): : 1689 - 1695
  • [44] Associations of the variation in the porcine myogenin gene with muscle fibre characteristics, lean meat production and meat quality traits
    Kim, J. M.
    Choi, B. D.
    Kim, B. C.
    Park, S. S.
    Hong, K. C.
    JOURNAL OF ANIMAL BREEDING AND GENETICS, 2009, 126 (02) : 134 - 141
  • [45] Molecular characterization, transcriptional regulation and association analysis with carcass traits of porcine TCAP gene
    Qiao, Mu
    Huang, Jingshu
    Wu, Huayu
    Wu, Junjing
    Peng, Xianwen
    Mei, Shuqi
    GENE, 2014, 538 (02) : 273 - 279
  • [46] Comparison between the three porcine RN genotypes for growth, carcass composition and meat quality traits
    Pascale Le Roy
    Jean-Michel Elsen
    Jean-Claude Caritez
    André Talmant
    Hervé Juin
    Pierre Sellier
    Gabriel Monin
    Genetics Selection Evolution, 32
  • [47] Comparison between the three porcine RN genotypes for growth, carcass composition and meat quality traits
    Le Roy, P
    Elsen, JM
    Caritez, JC
    Talmant, A
    Juin, H
    Sellier, P
    Monin, G
    GENETICS SELECTION EVOLUTION, 2000, 32 (02) : 165 - 186
  • [48] Association of N-terminal domain polymorphisms of the porcine glucocorticoid receptor with carcass composition and meat quality traits
    Reyer, Henry
    Ponsuksili, Siriluck
    Wimmers, Klaus
    Murani, Eduard
    ANIMAL GENETICS, 2014, 45 (01) : 125 - 129
  • [49] Polymorphisms of the SCD1 Gene and Its Association Analysis with Carcass, Meat Quality, Adipogenic Traits, Fatty Acid Composition, and Milk Production Traits in Cattle
    Liu, Ruimin
    Fang, Xibi
    Lu, Xin
    Liu, Yue
    Li, Yue
    Bai, Xue
    Ding, Xiangbin
    Yang, Runjun
    ANIMALS, 2024, 14 (12):
  • [50] Carnosine content in the porcine longissimus thoracis muscle and its association with meat quality attributes and carnosine-related gene expression
    D'Astous-Page, Joel
    Gariepy, Claude
    Blouin, Richard
    Cliche, Simon
    Sullivan, Brian
    Fortin, Frederic
    Palin, Marie-France
    MEAT SCIENCE, 2017, 124 : 84 - 94
12345