Association and expression analysis of porcine HNF1A gene related to meat and carcass quality traits

被引：8
作者：
Kayan, Autchara [1 ,2 ]
Uddin, Muhammad Jasim [1 ,3 ]
Kocamis, Hakan [4 ]
Tesfaye, Dawit [1 ]
Looft, Christian [1 ]
Tholen, Ernst [1 ]
Schellander, Karl [1 ]
Cinar, Mehmet Ulas [1 ]
机构：
[1] Univ Bonn, Inst Anim Sci, Anim Breeding & Husb Grp, D-53115 Bonn, Germany
[2] Kasetsart Univ, Fac Agr, Dapartment Anim Sci, Bangkok 10900, Thailand
[3] Bangladesh Agr Univ, Fac Vet Sci, Dept Med, Mymensingh 2202, Bangladesh
[4] Kirikkale Univ, Fac Vet, Dept Histol & Embryol, TR-71450 Kirikkale, Turkey
来源：
MEAT SCIENCE | 2013年 / 94卷 / 04期
关键词：
HNF1A; Single nucleotide polymorphism; mRNA and protein expression; Methylation; Meat quality; Pig; INTRAMUSCULAR FAT-CONTENT; ACID-COMPOSITION; DNA METHYLATION; QTL; IDENTIFICATION; HEPATOCYTE-NUCLEAR-FACTOR-1-ALPHA; POLYMORPHISMS; ACTIVATION; FATNESS; TARGET;
D O I：
10.1016/j.meatsci.2013.04.015
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
The aim of this study was to investigate the association and expression of HNF1A gene as a candidate gene for meat and carcass quality traits in pigs. Statistical analysis revealed that the g.8260 A>G polymorphism significantly associated with pH 24(H), meat percentage and muscle area in the F-2 Duroc x Pietrain (DuPi, n = 313) and with pH 24(L), fat area and backfat thickness in the Pietrain (Pi, n = 110) population. HNF1A mRNA and protein expressions were higher (p < 0.05) in animals with the low post-mortem muscle pH 24(L). The promoter methylation profiling suggested that methylation was not involved on HNF1A expression regulation (p > 0.05) in animal with divergent muscle pH. In conclusion, polymorphism in porcine HNF1A gene could be used as a candidate marker to improve the meat and carcass quality traits, with the consideration of breed-specific effect. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：474 / 479
页数：6
相关论文
共 50 条
  • [31] Sequence and haplotypes of ankyrin 1 gene (ANK1) and their association with carcass and meat quality traits in yak
    Hu, Jiang
    Gao, Xiaoli
    Shi, Bingang
    Chen, Haiqing
    Zhao, Zhidong
    Wang, Jiqing
    Liu, Xiu
    Li, Shaobin
    Luo, Yuzhu
    MAMMALIAN GENOME, 2021, 32 (02) : 104 - 114
  • [32] Molecular characterization, expression pattern, and association analysis with carcass traits of the porcine SHIP2 gene
    Qi Xiong
    Jin Chai
    Changyan Deng
    Siwen Jiang
    Xiaofeng Li
    Xiaojun Suo
    Nian Zhang
    Qianping Yang
    Yang Liu
    Rong Zheng
    Mingxin Chen
    Molecular and Cellular Biochemistry, 2012, 360 : 225 - 233
  • [33] Association of MC4R gene variants with carcass and meat quality traits in Qinchuan cattle
    Liu, Hongyu
    Tian, Wanqiang
    Zan, Linsen
    Wang, Hongbao
    Cui, Huan
    AFRICAN JOURNAL OF BIOTECHNOLOGY, 2009, 8 (15): : 3666 - 3671
  • [34] Effects of variation in porcine MYOD1 gene on muscle fiber characteristics, lean meat production, and meat quality traits
    Lee, E. A.
    Kim, J. M.
    Lim, K. S.
    Ryu, Y. C.
    Jeon, W. M.
    Hong, K. C.
    MEAT SCIENCE, 2012, 92 (01) : 36 - 43
  • [35] Association of Missense MTTP Gene Polymorphism with Carcass Characteristics and Meat Quality Traits in Pigs
    Ropka-Molik, Katarzyna
    Podstawski, Przemyslaw
    Piorkowska, Katarzyna
    Tyra, Miroslaw
    CZECH JOURNAL OF ANIMAL SCIENCE, 2017, 62 (01) : 9 - 14
  • [36] Molecular characterization, chromosomal localization, expression profile and association analysis with carcass traits of the porcine dickkopf homolog1 gene
    Liu, Chuxin
    Gao, Hui
    Zhai, Shanli
    Liu, Bang
    MOLECULAR BIOLOGY REPORTS, 2011, 38 (03) : 1929 - 1934
  • [37] Novel SNPs of the bovine CACNA2D1 gene and their association with carcass and meat quality traits
    Yuan, Zheng Rong
    Xu, Shang Zhong
    MOLECULAR BIOLOGY REPORTS, 2011, 38 (01) : 365 - 370
  • [38] Probiotics and Synbiotics Addition to Bama Mini-Pigs' Diet Improve Carcass Traits and Meat Quality by Altering Plasma Metabolites and Related Gene Expression of Offspring
    Zhu, Qian
    Song, Mingtong
    Azad, Md. Abul Kalam
    Ma, Cui
    Yin, Yulong
    Kong, Xiangfeng
    FRONTIERS IN VETERINARY SCIENCE, 2022, 9
  • [39] Association of DGAT2 gene polymorphisms with carcass and meat quality traits in domestic pigeons (Columba livia)
    Mao, H. G.
    Dong, X. Y.
    Cao, H. Y.
    Xu, N. Y.
    Yin, Z. Z.
    BRITISH POULTRY SCIENCE, 2018, 59 (02) : 149 - 153
  • [40] Integrated analysis of expression profiles with meat quality traits in cattle
    Li, Yunxiao
    Yang, Miaosen
    Lou, Angang
    Yun, Jinyan
    Ren, Chunyu
    Li, Xiangchun
    Xia, Guangjun
    Nam, Kichang
    Yoon, Duhak
    Jin, Haiguo
    Seo, Kangseok
    Jin, Xin
    SCIENTIFIC REPORTS, 2022, 12 (01)
12345