Primary percutaneous interventions into the coronary arteries in patients with diabetes mellitus

被引:1
作者
Bessonov, I. S. [1 ]
Kuznetsov, V. A. [1 ]
Zyryanov, I. P. [1 ]
Sapozhnikov, S. S. [1 ]
Musikhina, N. A. [1 ]
Rozhkov, A. G. [1 ]
机构
[1] Cardiol Res Inst, Tyumen Cardiol Ctr, Tyumen, Russia
关键词
myocardial infarction; primary percutaneous interventions into the coronary arteries; diabetes mellitus; ACUTE MYOCARDIAL-INFARCTION; PRIMARY ANGIOPLASTY; TERM; SURVIVAL; TRENDS; IMPACT;
D O I
10.17116/terarkh201688835-39
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aim. To investigate the specific features and results of percutaneous interventions (PCI) into the coronary arteries in patients with acute ST-segment elevation myocardial infarction (MI) and diabetes mellitus (DM) in clinical practice. Subjects and methods. A study group consisted of 120 patients with a history of type 2 DM, who had undergone primary PCI in 2008 to 2013. A comparison group included 601 patients without a history of DM. Results. Assessment of the results of hospital interventions revealed no differences between the study and comparison groups in mortality rates (4.1 and 3.2%, respectively; p=0.376), stent thromboses (0.8 and 1.2%, respectively; p=0.601), and recurrent MI (0 and 1.5%, respectively; p=0.189). No differences were determined in the combined index including death, recurrent MI, and stent thrombosis (5 and 5%; p=0.985). At the same time, the no-reflow phenomenon developed statistically significantly more frequently in the patients with DM (7.4 and 2.8%; p=0.019). Binary logistic regression established independent associations between the presence of DM and patient age (odds ratio (OR) 1.04; 95% confidence interval (CI) 1.02 to 1.07; p<0.001), female sex (OR 0.36; 95% CI 0.23 to 0.56; p<0.001), and higher body mass index (OR 1.1; 95% CI 1.06 to 1.16; p<0.04). Conclusion. Primary PCIs in patients with DM are an effective and safe method for revascularization in acute ST-segment elevation MI and these are not followed by increases in mortality and frequency of major poor cardiac complications at the hospital stage despite the more common development of the no-reflow phenomenon.
引用
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页码:35 / 39
页数:5
相关论文
共 11 条
[1]   Diabetes Mellitus, Myocardial Reperfusion, and Outcome in Patients With Acute ST-Elevation Myocardial Infarction Treated With Primary Angioplasty (from HORIZONS AMI) [J].
Brener, Sorin J. ;
Mehran, Roxana ;
Dressler, Ovidiu ;
Cristea, Ecaterina ;
Stone, Gregg W. .
AMERICAN JOURNAL OF CARDIOLOGY, 2012, 109 (08) :1111-1116
[2]  
Collet Jean-Philippe, 2005, Diab Vasc Dis Res, V2, P136, DOI 10.3132/dvdr.2005.021
[3]   Impact of Diabetes on Long-Term Outcome After Primary Angioplasty [J].
De Luca, Giuseppe ;
Dirksen, Maurits T. ;
Spaulding, Christian ;
Kelbk, Henning ;
Schalij, Martin ;
Thuesen, Leif ;
Van der Hoeven, Bas ;
Vink, Marteen A. ;
Kaiser, Christoph ;
Musto, Carmine ;
Chechi, Tania ;
Spaziani, Gaia ;
Salvador Diaz de la Llera, Luis ;
Pasceri, Vincenzo ;
Di Lorenzo, Emilio ;
Violini, Roberto ;
Suryapranata, Harry ;
Stone, Gregg W. .
DIABETES CARE, 2013, 36 (04) :1020-1025
[4]  
Ergelen M, 2010, J AM COLL CARDIOL, V55
[5]   Diabetes Mellitus and Trends in Hospital Survival After Myocardial Infarction, 1994 to 2006 Data From the National Registry of Myocardial Infarction [J].
Gore, M. Odette ;
Patel, Mahesh J. ;
Kosiborod, Mikhail ;
Parsons, Lori S. ;
Khera, Amit ;
de Lemos, James A. ;
Rogers, William J. ;
Peterson, Eric D. ;
Canto, John C. ;
McGuire, Darren K. .
CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES, 2012, 5 (06) :791-797
[6]   Long-Term Survival After Acute Myocardial Infarction and Relation to Type 2 Diabetes and Other Risk Factors [J].
Gruppetta, Mark ;
Calleja, Neville ;
Fava, Stephen .
CLINICAL CARDIOLOGY, 2010, 33 (07) :424-429
[7]   Impact of admission hyperglycemia and diabetes mellitus on short- and long-term mortality after acute myocardial infarction in the coronary intervention era [J].
Ishihara, Masaharu ;
Kagawa, Eisuke ;
Inoue, Ichiro ;
Kawagoe, Takuji ;
Shimatani, Yuji ;
Kurisu, Satoshi ;
Nakama, Yasuharu ;
Maruhashi, Tatsuya ;
Ookawa, Keisuke ;
Dai, Kazuoki ;
Aokage, Yasuyuki .
AMERICAN JOURNAL OF CARDIOLOGY, 2007, 99 (12) :1674-1679
[8]   Association of diabetes with increased all-cause mortality following primary percutaneous coronary intervention for ST-segment elevation myocardial infarction in the contemporary era [J].
Kahn, Matthew B. ;
Cubbon, Richard M. ;
Mercer, Ben ;
Wheatcroft, Alison C. G. ;
Gherardi, Guy ;
Aziz, Amir ;
Baliga, Vivek ;
Blaxill, Jonathan M. ;
McLenachan, Jim M. ;
Blackman, Daniel J. ;
Greenwood, John P. ;
Wheatcroft, Stephen B. .
DIABETES & VASCULAR DISEASE RESEARCH, 2012, 9 (01) :3-9
[9]   Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials [J].
Keeley, EC ;
Boura, JA ;
Grines, CL .
LANCET, 2003, 361 (9351) :13-20
[10]   5-Year Prognostic Value of No-Reflow Phenomenon After Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction [J].
Ndrepepa, Gjin ;
Tiroch, Klaus ;
Fusaro, Massimiliano ;
Keta, Dritan ;
Seyfarth, Melchior ;
Byrne, Robert A. ;
Pache, Juergen ;
Alger, Patricia ;
Mehilli, Julinda ;
Schoemig, Albert ;
Kastrati, Adnan .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2010, 55 (21) :2383-2389