Mechanistic Interpretation of Promoter-Proximal Peaks and RNAPII Density Maps

被引：90

作者：

Ehrensberger, Andreas H. ^{[1
]}

Kelly, Gavin P. ^{[2
]}

Svejstrup, Jesper Q. ^{[1
]}

机构：

[1] Canc Res UK London Res Inst, Clare Hall Labs, Mech Transcript Lab, S Mimms EN6 3LD, Herts, England

[2] Canc Res UK London Res Inst, Bioinformat & Biostat Grp, London WC2A 3LY, England

来源：

CELL | 2013年 / 154卷 / 04期

关键词：

HEAT-SHOCK; TRANSCRIPTION; ELONGATION; DROSOPHILA; GENES;

D O I：

10.1016/j.cell.2013.07.032

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：713 / 715

页数：3

共 10 条

[1] Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans [J].

Adelman, Karen ;

Lis, John T. .

NATURE REVIEWS GENETICS, 2012, 13 (10) :720-731

[2] Real-Time Observation of Transcription Initiation and Elongation on an Endogenous Yeast Gene [J].

Larson, Daniel R. ;

Zenklusen, Daniel ;

Wu, Bin ;

Chao, Jeffrey A. ;

Singer, Robert H. .

SCIENCE, 2011, 332 (6028) :475-478

[3] TRANSCRIPTION, EXPORT AND TURNOVER OF HSP70 AND ALPHA-BETA,2 DROSOPHILA HEAT-SHOCK GENES SHARING A 400 NUCLEOTIDE 5' UPSTREAM REGION [J].

LENGYEL, JA ;

GRAHAM, ML .

NUCLEIC ACIDS RESEARCH, 1984, 12 (14) :5719-5735

[4] Global Analysis of Short RNAs Reveals Widespread Promoter-Proximal Stalling and Arrest of Pol II in Drosophila [J].

Nechaev, Sergei ;

Fargo, David C. ;

dos Santos, Gilberto ;

Liu, Liwen ;

Gao, Yuan ;

Adelman, Karen .

SCIENCE, 2010, 327 (5963) :335-338

[5] RAPID CHANGES IN DROSOPHILA TRANSCRIPTION AFTER AN INSTANTANEOUS HEAT-SHOCK [J].

OBRIEN, T ;

LIS, JT .

MOLECULAR AND CELLULAR BIOLOGY, 1993, 13 (06) :3456-3463

[6] RNA POLYMERASE-II PAUSES AT THE 5' END OF THE TRANSCRIPTIONALLY INDUCED DROSOPHILA-HSP70 GENE [J].

OBRIEN, T ;

LIS, JT .

MOLECULAR AND CELLULAR BIOLOGY, 1991, 11 (10) :5285-5290

[7] c-Myc Regulates Transcriptional Pause Release [J].

Rahl, Peter B. ;

Lin, Charles Y. ;

Seila, Amy C. ;

Flynn, Ryan A. ;

McCuine, Scott ;

Burge, Christopher B. ;

Sharp, Phillip A. ;

Young, Richard A. .

CELL, 2010, 141 (03) :432-445

[8] Stability, Flexibility, and Dynamic Interactions of Colliding RNA Polymerase II Elongation Complexes [J].

Saeki, Hideaki ;

Svejstrup, Jesper Q. .

MOLECULAR CELL, 2009, 35 (02) :191-205

[9] Rates of in situ transcription and splicing in large human genes [J].

Singh, Jarnail ;

Padgett, Richard A. .

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2009, 16 (11) :1128-U1

[10] Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors [J].

Takahashi, Hidehisa ;

Parmely, Tari J. ;

Sato, Shigeo ;

Tomomori-Sato, Chieri ;

Banks, Charles A. S. ;

Kong, Stephanie E. ;

Szutorisz, Henrietta ;

Swanson, Selene K. ;

Martin-Brown, Skylar ;

Washburn, Michael P. ;

Florens, Laurence ;

Seidel, Chris W. ;

Lin, Chengqi ;

Smith, Edwin R. ;

Shilatifard, Ali ;

Conaway, Ronald C. ;

Conaway, Joan W. .

CELL, 2011, 146 (01) :92-104

← 1 →