Histone Serotonylation: Can the Brain Have "Happy'' Chromatin?

被引:16
作者
Anastas, Jamie N. [1 ,2 ,3 ]
Shi, Yang [1 ,2 ,3 ]
机构
[1] Boston Childrens Hosp, Dept Med, Div Newborn Med, Boston, MA 02115 USA
[2] Boston Childrens Hosp, Dept Med, Epigenet Program, Boston, MA 02115 USA
[3] Harvard Med Sch, Dept Cell Biol, Boston, MA 02115 USA
关键词
D O I
10.1016/j.molcel.2019.04.017
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recent work from Farrelly et al. (2019) indicates that histone tails can be serotonylated, suggesting a previously unappreciated direct mechanism of potential crosstalk between bioactive amines and the epigenome.
引用
收藏
页码:418 / 420
页数:3
相关论文
共 10 条
[1]   Core histones are glutaminyl substrates for tissue transglutaminase [J].
Ballestar, E ;
Abad, C ;
Franco, L .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (31) :18817-18824
[2]   The Expanded Biology of Serotonin [J].
Berger, Miles ;
Gray, John A. ;
Roth, Bryan L. .
ANNUAL REVIEW OF MEDICINE, 2009, 60 :355-366
[3]   Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3 [J].
Farrelly, Lorna A. ;
Thompson, Robert E. ;
Zhao, Shuai ;
Lepack, Ashley E. ;
Lyu, Yang ;
Bhanu, Natarajan V. ;
Zhang, Baichao ;
Loh, Yong-Hwee E. ;
Ramakrishnan, Aarthi ;
Vadodaria, Krishna C. ;
Heard, Kelly J. ;
Erikson, Galina ;
Nakadai, Tomoyoshi ;
Bastle, Ryan M. ;
Lukasak, Bradley J. ;
Zebroski, Henry, III ;
Alenina, Natalia ;
Bader, Michael ;
Berton, Olivier ;
Roeder, Robert G. ;
Molina, Henrik ;
Gage, Fred H. ;
Shen, Li ;
Garcia, Benjamin A. ;
Li, Haitao ;
Muir, Tom W. ;
Maze, Ian .
NATURE, 2019, 567 (7749) :535-+
[4]   SnapShot: Histone Modifications [J].
Huang, He ;
Sabari, Benjamin R. ;
Garcia, Benjamin A. ;
Allis, C. David ;
Zhao, Yingming .
CELL, 2014, 159 (02) :458-+
[5]   The microheterogeneity of the mammalian H10 histone -: Evidence for an age-dependent deamidation [J].
Lindner, H ;
Sarg, B ;
Hoertnagl, B ;
Helliger, W .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (21) :13324-13330
[6]   Transglutaminases: Crosslinking enzymes with pleiotropic functions [J].
Lorand, L ;
Graham, RM .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2003, 4 (02) :140-156
[7]   Signaling at G-protein-coupled serotonin receptors: recent advances and future research directions [J].
Millan, Mark J. ;
Marin, Philippe ;
Bockaert, Joel ;
la Cour, Clotilde Mannoury .
TRENDS IN PHARMACOLOGICAL SCIENCES, 2008, 29 (09) :454-464
[8]   Serotonylation and Transamidation of Other Monoamines [J].
Muma, Nancy A. ;
Mi, Zhen .
ACS CHEMICAL NEUROSCIENCE, 2015, 6 (07) :961-969
[9]   Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4 [J].
Vermeulen, Michiel ;
Mulder, Klaas W. ;
Denissov, Sergei ;
Pijnappel, W. W. M. Pim ;
van Schaik, Frederik M. A. ;
Varier, Radhika A. ;
Baltissen, Marijke P. A. ;
Stunnenberg, Henk G. ;
Mann, Matthias ;
Timmers, H. Th. Marc .
CELL, 2007, 131 (01) :58-69
[10]   Novel roles for biogenic monoamines: from monoamines in transglutaminase-mediated post-translational protein modification to monoaminylation deregulation diseases [J].
Walther, Diego J. ;
Stahlberg, Silke ;
Vowinckel, Jakob .
FEBS JOURNAL, 2011, 278 (24) :4740-4755