Coronary artery stenosis treatment in aging patients with inherited Factor VII deficiency: Where do we stand?

被引：2

作者：

Napolitano, Mariasanta ^{[1
]}

Siragusa, Sergio ^{[1
]}

机构：

[1] Univ Palermo, Thrombosis & Hemostasis Reference Reg Ctr, Haematol Unit, Via Vespro, I-97100 Palermo, Italy

来源：

TRANSFUSION AND APHERESIS SCIENCE | 2017年 / 56卷 / 06期

关键词：

Factor VII deficiency; Arterial thrombosis; Antiplatelet agents; Bleeding; Cardiovascular risk factors; THROMBOSIS; EFFICACY; SURGERY; THERAPY;

D O I：

10.1016/j.transci.2017.10.005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aging with rare bleeding disorders such as factor VII (FVII) deficiency poses several challenges to treatment because of the occurrence of cerebral and cardiovascular age-related comorbidities and high bleeding risks. We report a case of long-term treatment with antiplatelet agents and contemporary prophylaxis of bleeding in a woman affected by severe FVII deficiency diagnosed with symptomatic coronary artery stenosis. Information on the management of antithrombotic treatment in rare bleeding disorders is lacking and mainly limited to anecdotal reports or side effects secondary to replacement therapy. We also briefly reviewed available data on the treatment of arterial thrombosis in FVII deficiency. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：867 / 869

页数：3

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