Treatment for occult breast cancer: A propensity score analysis of the National Cancer Database

被引：14

作者：

Tsai, Catherine ^{[1
]}

Zhao, Beiqun ^{[1
]}

Chan, Theresa ^{[1
]}

Blair, Sarah L. ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Gen Surg, San Diego, CA 92103 USA

来源：

AMERICAN JOURNAL OF SURGERY | 2020年 / 220卷 / 01期

关键词：

Occult breast cancer; NCDB; Propensity score matching; Radiation therapy; Mastectomy; TREATMENT OUTCOMES; CARCINOMA; SURVIVAL; SURGERY; WOMEN; RADIOTHERAPY; METASTASES;

D O I：

10.1016/j.amjsurg.2019.11.023

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Background: Controversy exists regarding optimal treatment of occult breast cancer (OBC). Treatment options include mastectomy alone (MAST), radiation alone (XRT), or mastectomy with radiation (MXRT). Methods: We queried the National Cancer Database from 2004 to 2014 for patients with OBC who underwent MAST, XRT, or MXRT. We utilized propensity score matching to perform three head-to-head comparisons. Kaplan-Meier analysis was performed to compare overall survival (OS). Results: A total of 190 patients received XRT, 237 received MAST, and 244 received MXRT. In the MXRT vs. XRT comparison, 5-year OS was 78.2% and 82.8%, respectively. In the MXRT vs. MAST comparison, 5-year OS was 81.5% and 86.7%, respectively. In the MAST vs. XRT comparison, 5-year OS was 83.2% and 82.5%, respectively. There was no difference in OS for all paired comparisons. Conclusions: There were no OS differences in patients undergoing MAST, XRT, or MXRT, suggesting that breast conservation can be considered in patients with OBC. Published by Elsevier Inc.

引用

页码：153 / 160

页数：8

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