A Review of Primary Cutaneous CD30+ Lymphoproliferative Disorders

被引：13

作者：

Chen, Cynthia ^{[1
]}

Gu, Yuhan D. ^{[1
]}

Geskin, Larisa J. ^{[2
]}

机构：

[1] Columbia Univ, Vagelos Coll Phys & Surg, 161 Ft Washington Ave, New York, NY 10032 USA

[2] Columbia Univ, Dept Dermatol, 161 Ft Washington Ave, New York, NY 10032 USA

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2019年 / 33卷 / 01期

关键词：

CD30; Lymphoproliferative; LyP; pcALCL; CTCL; LARGE-CELL LYMPHOMA; TNM CLASSIFICATION-SYSTEM; MYCOSIS-FUNGOIDES; HODGKINS-DISEASE; EUROPEAN-ORGANIZATION; BRENTUXIMAB VEDOTIN; PERIPHERAL-BLOOD; INTERFERON-ALPHA; PAPULOSIS; BEXAROTENE;

D O I：

10.1016/j.hoc.2018.08.003

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Primary cutaneous CD30(+) lymphoproliferative diseases (LPDs) comprise a range of diseases (LyP, pcALCL, and borderline lesions) with broad histologic and phenotypical characteristics, although they all share the common feature of a favorable prognosis notwithstanding histology suggestive of a high-grade lymphoma. Given their cytomorphologic similarities, accurate diagnosis and workup are needed to differentiate these distinct entities in order to best use novel biologic therapies and avoid aggressive overtreatment. Moreover, although CD30(+) LPDs have a favorable prognosis, secondary malignancies should be considered as part of the initial evaluation, and patients should have ongoing surveillance.

引用

页码：121 / +

页数：15

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