Image-guided radiotherapy and -brachytherapy for cervical cancer

被引：34

作者：

Dutta, Suresh ^{[1
]}

Nam Phong Nguyen ^{[2
]}

Vock, Jacqueline ^{[3
]}

Kerr, Christine ^{[4
]}

Godinez, Juan ^{[5
]}

Bose, Satya ^{[2
]}

Jang, Siyoung ^{[6
]}

Chi, Alexander ^{[7
]}

Almeida, Fabio ^{[8
]}

Woods, William ^{[9
]}

Desai, Anand ^{[10
]}

David, Rick ^{[11
]}

Karlsson, Ulf Lennart ^{[12
]}

Altdorfer, Gabor ^{[13
]}

机构：

[1] Med & Radiat Oncol PA, San Antonio, TX USA

[2] Howard Univ, Dept Radiat Oncol, Washington, DC 20060 USA

[3] Lindenhofspital, Dept Radiat Oncol, Bern, Switzerland

[4] Ctr Val Aurelle, Dept Radiat Oncol, Montpellier, France

[5] Florida Radiat Oncol Grp, Dept Radiat Oncol, Jacksonville, FL USA

[6] Univ Arizona, Dept Radiat Oncol, Tucson, AZ 85721 USA

[7] W Virginia Univ, Dept Radiat Oncol, Morgantown, WV 26506 USA

[8] Southwest PET CT Inst, Tucson, AZ USA

[9] Richard A Henson Canc Inst, Dept Radiat Oncol, Salisbury, MD USA

[10] Akron City Hosp, Dept Radiat Oncol, Akron, OH USA

[11] Michael D Watchtel Canc Ctr, Dept Radiat Oncol, Oshkosh, WI USA

[12] Marshfield Clin Fdn Med Res & Educ, Dept Radiat Oncol, Marshfield, WI 54449 USA

[13] Camden Clark Canc Ctr, Dept Radiat Oncol, Parkersburg, WV USA

来源：

FRONTIERS IN ONCOLOGY | 2015年 / 5卷

关键词：

cervical cancer; IGRT; IGBT; normal tissue sparing; INTENSITY-MODULATED RADIOTHERAPY; POSITRON-EMISSION-TOMOGRAPHY; TANDEM-OVOID APPLICATORS; ADAPTIVE BRACHYTHERAPY; CONCURRENT CHEMORADIOTHERAPY; HELICAL TOMOTHERAPY; RADIATION-THERAPY; PDR BRACHYTHERAPY; FIXED FIELD; FDG-PET;

D O I：

10.3389/fonc.2015.00064

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Conventional radiotherapy for cervical cancer relies on clinical examination, 3-dimensional conformal radiotherapy (3D-CRT), and 2-dimensional intracavitary brachytherapy. Excellent local control and survival have been obtained for small early stage cervical cancer with definitive radiotherapy. For bulky and locally advanced disease, the addition of chemotherapy has improved the prognosis but toxicity remains significant. New imaging technology such as positron-emission tomography and magnetic resonance imaging has improved tumor delineation for radiotherapy planning. Image-guided radiotherapy (IGRT) may decrease treatment toxicity of whole pelvic radiation because of its potential for bone marrow, bowel, and bladder sparring.Tumor shrinkage during whole pelvic IGRT may optimize image-guided brachytherapy (IGBT), allowing for better local control and reduced toxicity for patients with cervical cancer. IGRT and IGBT should be integrated in future prospective studies for cervical cancer.

引用

页数：6

共 46 条

[21] Whole pelvic helical tomotherapy for locally advanced cervical cancer: technical implementation of IMRT with helical tomothearapy [J].