Rh(III)-Catalyzed intramolecular redox-neutral cyclization of alkenes via C-H activation

被引：97
|
作者：
Shi, Zhuangzhi [1 ]
Boultadakis-Arapinis, Melissa [1 ]
Koester, Dennis C. [1 ]
Glorius, Frank [1 ]
机构：
[1] Univ Munster, Inst Organ Chem, D-48149 Munster, Germany
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 20期
基金：
欧洲研究理事会;
关键词：
AROMATIC IMINES; EFFICIENT SYNTHESIS; BOND ACTIVATION; ANNULATION; INDOLIZIDINE; HYDROARYLATION; AGONIST; ALKYNES; ACID;
D O I：
10.1039/c4cc00029c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Biologically interesting fused oligocyclic lactams have been prepared via an intramolecular redox-neutral cyclization process. By the proper choice of the substrates with a wide variety of tethered olefins, the less favored C-H bond can be activated and functionalized. This C-H activation proceeds under mild conditions, obviates the need for external oxidants, and displays a broad scope with respect to the substituents.
引用
收藏
页码：2650 / 2652
页数：3
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