Long-Term Accidental Overdose of Levetiracetam in an Infant

被引：7

作者：

Ozkale, Yasemin ^{[1
]}

Ozkale, Murat ^{[1
]}

Saygi, Semra ^{[2
]}

Erol, Ilknur ^{[2
]}

机构：

[1] Baskent Univ, Fac Med, Dept Pediat, TR-01120 Adana, Turkey

[2] Baskent Univ, Fac Med, Div Child Neurol, TR-01120 Adana, Turkey

来源：

JOURNAL OF CHILD NEUROLOGY | 2014年 / 29卷 / 07期

关键词：

chronic overdosage; levetiracetam; epilepsy; anticonvulsant; antiepileptic drug; INTRAVENOUS LEVETIRACETAM; REFRACTORY EPILEPSY; PARTIAL SEIZURES; EFFICACY; CHILDREN; TOLERABILITY; MULTICENTER; SAFETY; MG;

D O I：

10.1177/0883073813480560

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Levetiracetam is one of the new anticonvulsant drugs that has a high therapeutic index and potential antiepileptogenic effects. Herein, we report a patient with multidrug refractory epilepsy and Ohtahara syndrome who was accidentally administered 300 mg/kg/d for 35 days by her mother. To our knowledge, there are only a few cases of accidental overdose of levetiracetam in pediatric patients reported in the literature, and this case study is the first to report such a high and long-term dose in an infant who showed no adverse effects.

引用

页码：959 / 961

页数：3

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