Atopic dermatitis and skin allergies - update and outlook

被引:30
作者
Wollenberg, A. [1 ]
Feichtner, K. [1 ]
机构
[1] Univ Munich, Dept Dermatol & Allergy, D-80337 Munich, Germany
关键词
atopic dermatitis; chronic urticaria; drug allergy; CHRONIC SPONTANEOUS URTICARIA; DENDRITIC CELLS; POSITION PAPER; PATCH TEST; HYPERSENSITIVITY REACTIONS; CONTACT-DERMATITIS; ECZEMA HERPETICUM; CLINICAL-FEATURES; PROACTIVE THERAPY; OBJECTIVE SCORAD;
D O I
10.1111/all.12324
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
During the last few years, an impressive amount of experimental studies and clinical trials have dealt with a variety of distinct topics in allergic skin diseases - especially atopic dermatitis. In this update, we discuss selected recent data that provide relevant insights into clinical and pathophysiological aspects of allergic skin diseases or discuss promising targets and strategies for the future treatment of skin allergy. This includes aspects of barrier malfunction and inflammation as well as the interaction of the cutaneous immune system with the skin microbiome and diagnostic procedures for working up atopic dermatitis patients. Additionally, contact dermatitis, urticaria, and drug reactions are addressed in this review. This update summarizes novel evidence, highlighting current areas of uncertainties and debates that will stimulate scientific discussions and research activities in the field of atopic dermatitis and skin allergies in the future.
引用
收藏
页码:1509 / 1519
页数:11
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