Diabetic ketoacidosis secondary to L-asparaginase in acute lymphoblastic leukaemia

被引:13
作者
Gifford, G. [1 ]
Milliken, S. [1 ]
Greenfield, J. [2 ,3 ]
机构
[1] St Vincents Publ Hosp, Dept Haematol, Sydney, NSW, Australia
[2] St Vincents Publ Hosp, Dept Endocrinol, Sydney, NSW, Australia
[3] Garvan Inst Med Res, Diabet & Obes Res Program, Sydney, NSW, Australia
关键词
leukaemia; L-asparaginase; hyperglycaemia; diabetes; diabetic ketoacidosis; insulin; THERAPY; MELLITUS;
D O I
10.1111/imj.12216
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We describe a case of severe hyperglycaemia resulting in diabetic ketoacidosis secondary to L-asparaginase. There are few reports of this potentially life-threatening complication, particularly in the English literature. Awareness and recognition of this preventable and manageable problem will improve safe delivery of this anti-leukaemic drug.
引用
收藏
页码:946 / 948
页数:3
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