Natural products for controlling hyperlipidemia: review

被引：88

作者：

El-Tantawy, Walid Hamdy ^{[1
]}

Temraz, Abeer ^{[2
,3
]}

机构：

[1] Natl Org Drug Control & Res, Cairo, Egypt

[2] Umm Al Qura Univ, Coll Pharm, Pharmacognosy Dept, Mecca, Saudi Arabia

[3] Al Azhar Univ, Fac Pharm Girls, Pharmacognosy Dept, Cairo, Egypt

来源：

ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY | 2019年 / 125卷 / 02期

关键词：

Hyperlipidemia; herbal extract; cardiovascular diseases; RED YEAST RICE; SERUM-CHOLESTEROL CONCENTRATIONS; GAMMA-ORYZANOL; PLANT STEROLS; BRAN OIL; ANTIOXIDANT ACTIVITIES; LIPID-LEVELS; DIET; POLICOSANOL; REDUCTION;

D O I：

10.1080/13813455.2018.1441315

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Hyperlipidemia is an abnormality of lipid metabolism, characterized by an elevation of total cholesterol, triglyceride, and low density lipoprotein-cholesterol, and/or a decreasing of high density lipoprotein cholesterol in circulating levels. Hyperlipidemia has been ranked as one of the greatest risk factors contributing to prevalence and severity of coronary heart diseases. Hyperlipidemia-associated lipid disorders are considered the cause of atherosclerotic cardiovascular disease. There has been a growing interest in natural products and their role in the maintenance and improvement of health and wellness. The cholesterol-lowering effect of dietary plants has been well studied and various natural products were shown to be helpful in lowering plasma cholesterol levels and encouraging safety profile. The main focus of this review is to describe what we know to date of natural products, along with their lipid-lowering mechanisms, which are either through inhibition of cholesterol absorption, inhibition of cholesterol synthesis or antioxidant mechanisms.

引用

页码：128 / 135

页数：8

共 76 条

[1] Scientific Opinion on the substantiation of health claims related to: anthocyanidins and proanthocyanidins (ID 1787, 1788, 1789, 1790, 1791); sodium alginate and ulva (ID 1873); vitamins, minerals, trace elements and standardised ginseng G115 extract (ID 8, 1673, 1674); vitamins, minerals, lysine and/or arginine and/or taurine (ID 6, 1676, 1677); plant-based preparation for use in beverages (ID 4210, 4211); Carica papaya L. (ID 2007); "fish protein" (ID 651); acidic water-based, non-alcoholic flavoured beverages containing calcium in the range of 0.3 to 0.8 mol per mol of acid with a pH not lower than 3.7 (ID 1170); royal jelly (ID 1225, 1226, 1227, 1228, 1230, 1231, 1326, 1328, 1329, 1982, 4696, 4697); foods low in cholesterol (ID 624); and foods low in trans-fatty acids (ID 672, 4333) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 [J].