Liberation of drugs from multi-wall carbon nanotube carriers

被引：49
作者：
Boncel, Slawomir [1 ]
Zajac, Piotr [1 ]
Koziol, Krzysztof K. K. [2 ]
机构：
[1] Silesian Tech Univ, Dept Organ Chem Bioorgan Chem & Biotechnol, PL-44100 Gliwice, Poland
[2] Univ Cambridge, Dept Mat Sci & Met, Cambridge CB2 3QZ, England
来源：
JOURNAL OF CONTROLLED RELEASE | 2013年 / 169卷 / 1-2期
基金：
欧洲研究理事会;
关键词：
Multi-wall carbon nanotubes; Oxidised multi-wall carbon nanotubes; Drug conjugates; Drug delivery; Drug release kinetics; Drug release mechanism; RELEASE; NANOMATERIALS; TECHNOLOGY; COMPOSITE; CHEMISTRY; HYDROGELS; SCIENCE; PH;
D O I：
10.1016/j.jconrel.2013.04.009
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
MWCNTs in the 'nanotube-drug' hybrids can play a role of carriers or additives (enhancers) in the more complex formulations. This work reviews qualitative and quantitative analyses of Drug Delivery Systems (DDSs) based on multi-wall carbon nanotubes (MWCNTs) and their chemically modified analogues (mainly oxidised MWCNTs). A special emphasis was placed on the chemical interactions between drug molecules and the nanotube carrier critical both in the stage of preparation/synthesis of the hybrids and liberation of the drug. (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码：126 / 140
页数：15
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