(Poly)Combing the Pediatric Cancer Genome for Answers

被引：9

作者：

Morgan, Marc Alard ^{[1
]}

Shilatifard, Ali ^{[1
]}

机构：

[1] Stowers Inst Med Res, Kansas City, MO 64110 USA

来源：

SCIENCE | 2013年 / 340卷 / 6134期

关键词：

HISTONE; PRC2;

D O I：

10.1126/science.1239223

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：823 / 824

页数：2

共 15 条

[1] The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression [J].

Chan, Kui-Ming ;

Fang, Dong ;

Gan, Haiyun ;

Hashizume, Rintaro ;

Yu, Chuanhe ;

Schroeder, Mark ;

Gupta, Nalin ;

Mueller, Sabine ;

James, C. David ;

Jenkins, Robert ;

Sarkaria, Jann ;

Zhang, Zhiguo .

GENES & DEVELOPMENT, 2013, 27 (09) :985-990

[2] Histone H3K27ac separates active from poised enhancers and predicts developmental state [J].

Creyghton, Menno P. ;

Cheng, Albert W. ;

Welstead, G. Grant ;

Kooistra, Tristan ;

Carey, Bryce W. ;

Steine, Eveline J. ;

Hanna, Jacob ;

Lodato, Michael A. ;

Frampton, Garrett M. ;

Sharp, Phillip A. ;

Boyer, Laurie A. ;

Young, Richard A. ;

Jaenisch, Rudolf .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (50) :21931-21936

[3] The Pediatric Cancer Genome Project [J].

Downing, James R. ;

Wilson, Richard K. ;

Zhang, Jinghui ;

Mardis, Elaine R. ;

Pui, Ching-Hon ;

Ding, Li ;

Ley, Timothy J. ;

Evans, William E. .

NATURE GENETICS, 2012, 44 (06) :619-622

[4] Structural basis of LSD1-CoREST selectivity in histone H3 recognition [J].

Forneris, Federico ;

Binda, Claudia ;

Adamo, Antonio ;

Battaglioli, Elena ;

Mattevi, Andrea .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (28) :20070-20074

[5] Histone modification: cause or cog? [J].

Henikoff, Steven ;

Shilatifard, Ali .

TRENDS IN GENETICS, 2011, 27 (10) :389-396

[6] Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4 [J].

Herz, Hans-Martin ;

Mohan, Man ;

Garruss, Alexander S. ;

Liang, Kaiwei ;

Takahashi, Yoh-hei ;

Mickey, Kristen ;

Voets, Olaf ;

Verrijzer, C. Peter ;

Shilatifard, Ali .

GENES & DEVELOPMENT, 2012, 26 (23) :2604-2620

[7] The H3K27me3 Demethylase dUTX Is a Suppressor of Notch- and Rb-Dependent Tumors in Drosophila [J].

Herz, Hans-Martin ;

Madden, Laurence D. ;

Chen, Zhihong ;

Bolduc, Clare ;

Buff, Eugene ;

Gupta, Ravi ;

Davuluri, Ramana ;

Shilatifard, Ali ;

Hariharan, Iswar K. ;

Bergmann, Andreas .

MOLECULAR AND CELLULAR BIOLOGY, 2010, 30 (10) :2485-2497

[8] Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma [J].

Lewis, Peter W. ;

Mueller, Manuel M. ;

Koletsky, Matthew S. ;

Cordero, Francisco ;

Lin, Shu ;

Banaszynski, Laura A. ;

Garcia, Benjamin A. ;

Muir, Tom W. ;

Becher, Oren J. ;

Allis, C. David .

SCIENCE, 2013, 340 (6134) :857-861

[9] The Polycomb complex PRC2 and its mark in life [J].

Margueron, Raphael ;

Reinberg, Danny .

NATURE, 2011, 469 (7330) :343-349

[10] A Histone Mutant Reproduces the Phenotype Caused by Loss of Histone-Modifying Factor Polycomb [J].

Pengelly, Ana Raquel ;

Copur, Oemer ;

Jaeckle, Herbert ;

Herzig, Alf ;

Mueller, Juerg .

SCIENCE, 2013, 339 (6120) :698-699

← 1 2 →