The PROSITE database, its status in 2002

被引:839
作者
Falquet, L
Pagni, M
Bucher, P [1 ]
Hulo, N
Sigrist, CJA
Hofmann, K
Bairoch, A
机构
[1] Swiss Inst Expt Canc Res, Swiss Inst Bioinformat, CH-1066 Epalinges, Switzerland
[2] Univ Geneva, CMU, SIB, CH-1211 Geneva 4, Switzerland
[3] Stoffel GmbH, MEMOREC, D-50829 Cologne, Germany
关键词
D O I
10.1093/nar/30.1.235
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
PROSITE [Bairoch and Bucher (1994) Nucleic Acids Res., 22, 3583-3589; Hofmann et al. (1999) Nucleic Acids Res., 27, 215-219] is a method of identifying the functions of uncharacterized proteins translated from genomic or cDNA sequences. The PROSITE database (http://www.expasy.org/prosite/) consists of biologically significant patterns and profiles designed in such a way that with appropriate computational tools it can rapidly and reliably help to determine to which known family of proteins (if any) a new sequence belongs, or which known domain(s) it contains.
引用
收藏
页码:235 / 238
页数:4
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