The importance of hydrophobic moieties in ice recrystallization inhibitors

被引：51

作者：

Balcerzak, Anna K. ^{[1
]}

Febbraro, Michela ^{[1
]}

Ben, Robert N. ^{[1
]}

机构：

[1] Univ Ottawa, Dept Chem, Ottawa, ON K1N 6N5, Canada

来源：

RSC ADVANCES | 2013年 / 3卷 / 10期

基金：

加拿大健康研究院; 加拿大自然科学与工程研究理事会;

关键词：

MOLECULAR-WEIGHT GELATORS; STEM-CELL TRANSPLANTATION; UMBILICAL-CORD BLOOD; ANTIFREEZE GLYCOPROTEINS; NUCLEATING ACTIVITY; CRYSTAL-GROWTH; CD34(+) CELLS; L-LYSINE; CRYOPRESERVATION; DERIVATIVES;

D O I：

10.1039/c3ra23220d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Structurally diverse lysine-based surfactants/gelators and anti-ice nucleating agents (anti-INAs) were investigated as ice recrystallization inhibitors (IRIs). The results indicate that long alkyl chains are important for potent IRI activity and that the position of these alkyl chains is essential. Additionally, no correlation was found between IRI activity and critical micelle concentrations, gelation or anti-ice nucleation activity, although the counterion of some lysine surfactants did affect IRI activity.

引用

页码：3232 / 3236

页数：5

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