Sequence analysis of the X-linked USP26 gene in severe male factor infertility patients and fertile controls

被引:19
作者
Christensen, Greg L. [1 ]
Griffin, Jeanine [1 ]
Carrell, Douglas T. [1 ,2 ,3 ,4 ]
机构
[1] Univ Utah, Sch Med, Androl & IVF Labs, Salt Lake City, UT 84108 USA
[2] Univ Utah, Sch Med, Dept Surg, Salt Lake City, UT 84108 USA
[3] Univ Utah, Sch Med, Dept Obstet & Gynecol, Salt Lake City, UT 84108 USA
[4] Univ Utah, Sch Med, Dept Physiol, Salt Lake City, UT 84108 USA
关键词
D O I
10.1016/j.fertnstert.2007.06.096
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The 1090C>T,L364F variant of the ubiquitin protease 26 (USP26) gene does not appear to be related to male infertility. Mutations of the USP26 gene do not appear to be a common cause of idiopathic azoospermia or severe oligozoospermia.
引用
收藏
页码:851 / 852
页数:2
相关论文
共 7 条
[1]   Mechanism and function of deubiquitinating enzymes [J].
Amerik, AY ;
Hochstrasser, M .
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2004, 1695 (1-3) :189-207
[2]   A genomic and functional inventory of deubiquitinating enzymes [J].
Nijman, SMB ;
Luna-Vargas, MPA ;
Velds, A ;
Brummelkamp, TR ;
Dirac, AMG ;
Sixma, TK ;
Bernards, R .
CELL, 2005, 123 (05) :773-786
[3]  
Paduch DA, 2005, REPROD BIOMED ONLINE, V10, P747
[4]   Haplotypes, mutations and male fertility:: the story of the testis-specific ubiquitin protease USP26 [J].
Ravel, C. ;
El Houate, B. ;
Chantot, S. ;
Lourenco, D. ;
Dumaine, A. ;
Rouba, H. ;
Bandyopadahyay, A. ;
Radhakrishna, U. ;
Das, B. ;
Sengupta, S. ;
Mandelbaum, J. ;
Siffroi, J. P. ;
McElreavey, K. .
MOLECULAR HUMAN REPRODUCTION, 2006, 12 (10) :643-646
[5]   Possible role of USP26 in patients with severely impaired spermatogenesis [J].
Stouffs, K ;
Lissens, W ;
Tournaye, H ;
Van Steirteghem, A ;
Liebaers, I .
EUROPEAN JOURNAL OF HUMAN GENETICS, 2005, 13 (03) :336-340
[6]   Alterations of the USP26 gene in Caucasian men [J].
Stouffs, Katrien ;
Lissens, Willy ;
Tournaye, Herman ;
Van Steirteghem, Andre ;
Liebaers, Inge .
INTERNATIONAL JOURNAL OF ANDROLOGY, 2006, 29 (06) :614-617
[7]   An abundance of X-linked genes expressed in spermatogonia [J].
Wang, PJ ;
McCarrey, JR ;
Yang, F ;
Page, DC .
NATURE GENETICS, 2001, 27 (04) :422-426