Moving Successful Virus-specific T-cell Therapy for Hematopoietic Stem Cell Recipients to Late Phase Clinical Trials

被引:9
作者
Rooney, Cliona [1 ,2 ,3 ,4 ]
Leen, Ann [1 ,2 ,3 ]
机构
[1] Texas Childrens Hosp, Baylor Coll Med, Methodist Hosp, Ctr Cell & Gene Therapy, Houston, TX 77030 USA
[2] Baylor Coll Med, Dept Pediat, Houston, TX 77030 USA
[3] Baylor Coll Med, Dept Pathol, Houston, TX 77030 USA
[4] Baylor Coll Med, Dept Mol Virol & Microbiol, Houston, TX 77030 USA
关键词
ADOPTIVE TRANSFER; LYMPHOPROLIFERATIVE DISEASE; VIRAL-INFECTIONS; CYTOMEGALOVIRUS; TRANSPLANT; LYMPHOCYTES; RECONSTITUTION; PREVENTION; LYMPHOMA; CHILDREN;
D O I
10.1038/mtna.2012.49
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
[No abstract available]
引用
收藏
页数:4
相关论文
共 29 条
[21]   Reversible HLA multimers (Streptamers) for the isolation of human cytotoxic T lymphocytes functionally active against tumor- and virus-derived antigens [J].
Neudorfer, Julia ;
Schmidt, Burkhard ;
Huster, Katharina M. ;
Anderl, Florian ;
Schiemann, Matthias ;
Holzapfel, Gerd ;
Schmidt, Thomas ;
Germeroth, Lothar ;
Wagner, Hermann ;
Peschel, Christian ;
Busch, Dirk H. ;
Bernhard, Helga .
JOURNAL OF IMMUNOLOGICAL METHODS, 2007, 320 (1-2) :119-131
[22]   Rapid generation of combined CMV-specific CD4+ and CD8+ T-cell lines for adoptive transfer into recipients of allogeneic stem cell transplants [J].
Rauser, G ;
Einsele, H ;
Sinzger, C ;
Wernet, D ;
Kuntz, G ;
Assenmacher, M ;
Campbell, JDM ;
Topp, MS .
BLOOD, 2004, 103 (09) :3565-3572
[23]   Changing epidemiology of respiratory viral infections in hematopoietic cell transplant recipients and solid organ transplant recipients [J].
Renaud, Christian ;
Campbell, Angela P. .
CURRENT OPINION IN INFECTIOUS DISEASES, 2011, 24 (04) :333-343
[24]   Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients [J].
Rooney, CM ;
Smith, CA ;
Ng, CYC ;
Loftin, SK ;
Sixbey, JW ;
Gan, YJ ;
Srivastava, DK ;
Bowman, LC ;
Krance, RA ;
Brenner, MK ;
Heslop, HE .
BLOOD, 1998, 92 (05) :1549-1555
[25]   USE OF GENE-MODIFIED VIRUS-SPECIFIC T-LYMPHOCYTES TO CONTROL EPSTEIN-BARR-VIRUS-RELATED LYMPHOPROLIFERATION [J].
ROONEY, CM ;
SMITH, CA ;
NG, CYC ;
LOFTIN, S ;
LI, CF ;
KRANCE, RA ;
BRENNER, MK ;
HESLOP, HE .
LANCET, 1995, 345 (8941) :9-13
[26]   Adoptive transfer and selective reconstitution of streptamer-selected cytomegalovirus-specific CD8+ T cells leads to virus clearance in patients after allogeneic peripheral blood stem cell transplantation [J].
Schmitt, Anita ;
Tonn, Torsten ;
Busch, Dirk H. ;
Grigoleit, Goetz Ulrich ;
Einsele, Hermann ;
Odendahl, Marcus ;
Germeroth, Lothar ;
Ringhoffer, Mark ;
Ringhoffer, Simone ;
Wiesneth, Markus ;
Greiner, Jochen ;
Michel, Detlef ;
Mertens, Thomas ;
Rojewski, Markus ;
Marx, Martin ;
von Harsdorf, Stephanie ;
Doehner, Hartmut ;
Seifried, Erhard ;
Bunjes, Donald ;
Schmitt, Michael .
TRANSFUSION, 2011, 51 (03) :591-599
[27]   Prospective, Comprehensive, and Effective Viral Monitoring in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation [J].
Schoenberger, S. ;
Meisel, R. ;
Adams, O. ;
Pufal, Y. ;
Laws, H. J. ;
Enczmann, J. ;
Dilloo, D. .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2010, 16 (10) :1428-1435
[28]   Accelerated Production of Antigen-specific T Cells for Preclinical and Clinical Applications Using Gas-permeable Rapid Expansion Cultureware (G-Rex) [J].
Vera, Juan F. ;
Brenner, Lara J. ;
Gerdemann, Ulrike ;
Ngo, Minhtran C. ;
Sili, Uluhan ;
Liu, Hao ;
Wilson, John ;
Dotti, Gianpietro ;
Heslop, Helen E. ;
Leen, Ann M. ;
Rooney, Cliona M. .
JOURNAL OF IMMUNOTHERAPY, 2010, 33 (03) :305-315
[29]   RECONSTITUTION OF CELLULAR-IMMUNITY AGAINST CYTOMEGALOVIRUS IN RECIPIENTS OF ALLOGENEIC BONE-MARROW BY TRANSFER OF T-CELL CLONES FROM THE DONOR [J].
WALTER, EA ;
GREENBERG, PD ;
GILBERT, MJ ;
FINCH, RJ ;
WATANABE, KS ;
THOMAS, ED ;
RIDDELL, SR .
NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (16) :1038-1044