The Menin Inhibitor SNDX-5613 (revumenib) Leads to Durable Responses in Patients (Pts) with KMT2A-Rearranged or NPM1 Mutant AML: Updated Results of a Phase (Ph) 1 Study

被引：33

作者：

Issa, Ghayas C. ^{[1
]}

Aldoss, Ibrahim ^{[2
]}

DiPersio, John F. ^{[3
]}

Cuglievan, Branko ^{[4
]}

Stone, Richard M. ^{[5
]}

Arellano, Martha L. ^{[6
]}

Thirman, Michael J. ^{[7
]}

Patel, Manish R. ^{[8
]}

Dickens, David ^{[9
]}

Shenoy, Shalini ^{[10
]}

Shukla, Neerav ^{[11
]}

Rosen, Galit ^{[12
]}

Bagley, Rebecca G. ^{[12
]}

Meyers, Michael L. ^{[12
]}

Madigan, Kate ^{[12
]}

Ordentlich, Peter ^{[12
]}

Gu, Yu ^{[12
]}

Smith, Steven ^{[12
]}

McGeehan, Gerard M. ^{[12
]}

Stein, Eytan ^{[13
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX 77030 USA

[2] City Hope Natl Med Ctr, Duarte, CA USA

[3] Washington Univ, Sch Med, Dept Internal Med, Div Oncol, St Louis, MO 63110 USA

[4] Univ Texas MD Anderson Canc Ctr, Div Pediat Hematol Oncol, Houston, TX 77030 USA

[5] Dana Farber Canc Inst, Ctr Leukemia, Dept Med Oncol, Boston, MA 02115 USA

[6] Emory Univ, Sch Med, Winship Canc Inst, Atlanta, GA USA

[7] Univ Chicago, Dept Med, Sect Hematol Oncol, 5841 S Maryland Ave, Chicago, IL 60637 USA

[8] Sarah Cannon Res Inst, Florida Canc Specialists, Sarasota, FL USA

[9] Univ Iowa, Div Pediat Hematol & Oncol, Iowa City, IA USA

[10] Washington Univ, Sch Med, Dept Pediat, St Louis, MO 63110 USA

[11] Mem Sloan Kettering Canc Ctr, Dept Pediat, Pediat Hematol Oncol PD, 1275 York Ave, New York, NY 10021 USA

[12] Syndax Pharmaceut Inc, Waltham, MA USA

[13] Mem Sloan Kettering Canc Ctr, Dept Med, Leukemia Serv, 1275 York Ave, New York, NY 10021 USA

来源：

关键词：

D O I：

10.1182/blood-2022-164849

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：3