Lymphatic abnormalities in the normal contralateral arms of subjects with breast cancer-related lymphedema as assessed by near-infrared fluorescent imaging

被引：48

作者：

Aldrich, Melissa B. ^{[1
]}

Guilliod, Renie ^{[2
]}

Fife, Caroline E. ^{[2
]}

Maus, Erik A. ^{[2
]}

Smith, Latisha ^{[2
]}

Rasmussen, John C. ^{[1
]}

Sevick-Muraca, Eva M. ^{[1
]}

机构：

[1] Univ Texas Hlth Sci Ctr Houston, Brown Fdn Inst Mol Med, Ctr Mol Imaging, Houston, TX 77030 USA

[2] Mem Hermann Hosp, Mem Hermann Ctr Wound Healing, Houston, TX 77030 USA

来源：

BIOMEDICAL OPTICS EXPRESS | 2012年 / 3卷 / 06期

基金：

美国国家卫生研究院;

关键词：

LOWER-LIMB LYMPHEDEMA; NODE DISSECTION; RISK-FACTORS; MELANOMA; LYMPHOGRAPHY; HEALTHY; TRIAL;

D O I：

10.1364/BOE.3.001256

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Current treatment of unilateral breast cancer-related lymphedema (BCRL) is only directed to the afflicted arm. Near-infrared fluorescent imaging (NIRF) of arm lymphatic vessel architecture and function in BCRL and control subjects revealed a trend of increased lymphatic abnormalities in both the afflicted and unafflicted arms with increasing time after lymphedema onset. These pilot results show that BCRL may progress to affect the clinically "normal" arm, and suggest that cancer-related lymphedema may become a systemic, rather than local, malady. These findings support further study to understand the etiology of cancer-related lymphedema and lead to better diagnostics and therapeutics directed to the systemic lymphatic system. (C) 2012 Optical Society of America

引用

页码：1256 / 1265

页数：10

共 38 条

[1] Direct evidence of lymphatic function improvement after advanced pneumatic compression device treatment of lymphedema [J].

Adams, Kristen E. ;

Rasmussen, John C. ;

Darne, Chinmay ;

Tan, I-Chih ;

Aldrich, Melissa B. ;

Marshall, Milton V. ;

Fife, Caroline E. ;

Maus, Erik A. ;

Smith, Latisha A. ;

Guilloid, Renie ;

Hoy, Sunday ;

Sevick-Muraca, Eva M. .

BIOMEDICAL OPTICS EXPRESS, 2010, 1 (01) :114-125

[2] ILIOINGUINAL LYMPH NODE DISSECTION FOR PALPABLE METASTATIC MELANOMA TO THE GROIN [J].

Allan, Christopher P. ;

Hayes, Andrew J. ;

Thomas, J. Meirion .

ANZ JOURNAL OF SURGERY, 2008, 78 (11) :982-986

[3]

Armer JM, 2010, LYMPHOLOGY, V43, P118

[4] Lymphatic Dysfunction in the Apparently Clinically Normal Contralateral Limbs of Patients With Unilateral Lower Limb Swelling [J].

Burnand, Katherine M. ;

Glass, Daphne M. ;

Mortimer, Peter S. ;

Peters, Adrien Michael .

CLINICAL NUCLEAR MEDICINE, 2012, 37 (01) :9-13

[5] Prospective Assessment of Postoperative Complications and Associated Costs Following Inguinal Lymph Node Dissection (ILND) in Melanoma Patients [J].

Chang, Sharon B. ;

Askew, Robert L. ;

Xing, Yan ;

Weaver, Storm ;

Gershenwald, Jeffrey E. ;

Lee, Jeffrey E. ;

Royal, Richard ;

Lucci, Anthony ;

Ross, Merrick I. ;

Cormier, Janice N. .

ANNALS OF SURGICAL ONCOLOGY, 2010, 17 (10) :2764-2772

[6] Feasibility of Interstitial CT Lymphography Using Optimized Iodized Oil Emulsion in Rats [J].

Chung, Yong Eun ;

Hyung, Woo Jin ;

Kweon, Soonjae ;

Lim, Soo-Jeong ;

Choi, Junjeong ;

Lee, Myun Hee ;

Kim, Hoguen ;

Myoung, Sungmin ;

Lim, Joon Seok .

INVESTIGATIVE RADIOLOGY, 2010, 45 (03) :142-148

[7] Life after Breast Cancer: Dealing with Lymphoedema [J].

Cidon, Esther Una ;

Perea, Christian ;

Lopez-Lara, Francisco .

CLINICAL MEDICINE INSIGHTS-ONCOLOGY, 2011, 5 :9-14

[8]

Cooper Garry, 2010, Nurs Times, V106, P15

[9] Lymphedema Beyond Breast Cancer [J].

Cormier, Janice N. ;

Askew, Robert L. ;

Mungovan, Kristi S. ;

Xing, Yan ;

Ross, Merrick I. ;

Armer, Jane M. .

CANCER, 2010, 116 (22) :5138-5149

[10]

Daley SK, 2010, LYMPHOLOGY, V43, P48

← 1 2 3 4 →