Searching for Novel Cancer Chemopreventive Plants and their Products: The Genus Zanthoxylum

被引：40
作者：
Epifano, Francesco [1 ]
Curini, Massimo [2 ]
Marcotullio, Maria Carla [2 ]
Genovese, Salvatore [1 ]
机构：
[1] Univ G dAnnunzio, Dipartimento Sci Farm, I-66013 Chieti, CH, Italy
[2] Univ Perugia, Sez Chim Organ, Dipartimento Chim & Tecnol Farm, I-06123 Perugia, Italy
来源：
CURRENT DRUG TARGETS | 2011年 / 12卷 / 13期
关键词：
Anti-cancer activity; cancer chemoprevention; edible plants; prenyloxyphenylpropanoids; Rutaceae; Zanthoxylum; CYTOTOXIC CONSTITUENTS; MEDICINAL-PLANTS; OIL COMPOSITION; STEM BARK; SCHINIFOLIUM; FAGARONINE; MONTEVERDE; AURAPTENE; RHESTA; CELLS;
D O I：
10.2174/138945011798184128
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The genus Zanthoxylum (Rutaceae) comprises about 250 species, of which many are used as food, often as condiments, substituting pepper due to the pungent taste of fruits, seeds, leaves, and bark, and therapeutic remedies especially in Eastern Asian countries and in Central America. The whole plant is also consumed as an ingredient of soups and salads. The aim of this review is to examine in detail from a phytochemical and pharmacological point of view what is reported in the current literature about the anti-cancer and chemopreventive properties of phytopreparations or individual active compounds obtained from edible plants belonging to this genus.
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页码：1895 / 1902
页数：8
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