Tumor Necrosis Factor-α Inhibitor Use Is Not Associated with Lipid Changes in Rheumatoid Arthritis

被引：4

作者：

Bili, Androniki ^{[1
]}

Morris, Stephanie J. ^{[1
]}

Sartorius, Jennifer A. ^{[1
]}

Kirchner, H. Les ^{[1
]}

Antohe, Jana L. ^{[1
]}

Dancea, Sorina ^{[1
]}

Wasko, Mary Chester ^{[1
]}

机构：

[1] Geisinger Hlth Syst, Dept Rheumatol, Danville, PA 17822 USA

来源：

JOURNAL OF RHEUMATOLOGY | 2012年 / 39卷 / 05期

关键词：

RHEUMATOID ARTHRITIS; LIPIDS; TUMOR NECROSIS FACTOR-alpha INHIBITORS; INFLIXIMAB TREATMENT; INSULIN-RESISTANCE; PROFILE; THERAPY; PATTERNS;

D O I：

10.3899/jrheum.111093

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective. To determine the association of use of tumor necrosis factor-alpha (TNF-alpha) inhibitors with differences in lipid levels in patients with rheumatoid arthritis (RA). Methods. We studied 807 patients with incident RA to compare differences in lipid levels in TNF-alpha inhibitor users versus nonusers, with adjustment for relevant covariables. Results. TNF-alpha inhibitor use was not associated with differences in levels of low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol (TC), triglycerides, LDL:HDL, or TC:HDL compared to nonusers. Conclusion. Use of TNF-alpha inhibitor was not associated with differences in lipid levels in patients with RA. (First Release April 1 2012; J Rheumatol 2012;39:946-8; doi:10.3899/jrheum.111093)

引用

页码：946 / 948

页数：3

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