Tumor Necrosis Factor-α Inhibitor Use Is Not Associated with Lipid Changes in Rheumatoid Arthritis

被引：4
作者：
Bili, Androniki [1 ]
Morris, Stephanie J. [1 ]
Sartorius, Jennifer A. [1 ]
Kirchner, H. Les [1 ]
Antohe, Jana L. [1 ]
Dancea, Sorina [1 ]
Wasko, Mary Chester [1 ]
机构：
[1] Geisinger Hlth Syst, Dept Rheumatol, Danville, PA 17822 USA
来源：
JOURNAL OF RHEUMATOLOGY | 2012年 / 39卷 / 05期
关键词：
RHEUMATOID ARTHRITIS; LIPIDS; TUMOR NECROSIS FACTOR-alpha INHIBITORS; INFLIXIMAB TREATMENT; INSULIN-RESISTANCE; PROFILE; THERAPY; PATTERNS;
D O I：
10.3899/jrheum.111093
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objective. To determine the association of use of tumor necrosis factor-alpha (TNF-alpha) inhibitors with differences in lipid levels in patients with rheumatoid arthritis (RA). Methods. We studied 807 patients with incident RA to compare differences in lipid levels in TNF-alpha inhibitor users versus nonusers, with adjustment for relevant covariables. Results. TNF-alpha inhibitor use was not associated with differences in levels of low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol (TC), triglycerides, LDL:HDL, or TC:HDL compared to nonusers. Conclusion. Use of TNF-alpha inhibitor was not associated with differences in lipid levels in patients with RA. (First Release April 1 2012; J Rheumatol 2012;39:946-8; doi:10.3899/jrheum.111093)
引用
收藏
页码：946 / 948
页数：3
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