Role and expression patterns of E-cadherin in head and neck squamous cell carcinoma (HNSCC)

被引：1
|
作者：
Georgolios, A
Batistatou, A
Manolopoulos, L
Charalabopoulos, K
机构：
[1] Univ Ioannina, Fac Med, Dept Physiol, Clin Unit, GR-45110 Ioannina, Greece
[2] Univ Ioannina, Fac Med, Dept Pathol, GR-45110 Ioannina, Greece
[3] Univ Athens, Fac Med, Dept Otolaryngol, Athens, Greece
来源：
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH | 2006年 / 25卷 / 01期
关键词：
E-cadherin; cancer; head and neck squamous cell carcinoma; adhesion molecules;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
E- cadherin is a member of the cadherin superfamily known as the main mediator of the cell- cell calcium dependent adhesion interactions. Research evidence also yields to this adhesion molecule an Important role in carcinogenesis and tumor progression. This review focuses on the differential expression of E- cadherin in the various anatomic sites of the human body where HNSCC arises. Controversies in the results of various studies are discussed and possible prospects for application of all this developing knowledge to prognosis and therapy of the disease are briefly mentioned.
引用
收藏
页码：5 / 14
页数：10
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