1:1 atrial-flutter. Prevalence and clinical characteristics

被引:11
作者
Brembilla-Perrot, Beatrice [1 ]
Laporte, Franck [1 ]
Sellal, Jean Marc [1 ]
Schwartz, Jerome [1 ]
Olivier, Arnaud [1 ]
Zinzius, Pierre Yves [1 ]
Manenti, Vladimir [1 ]
Beurrier, Daniel [1 ]
Andronache, Marius [1 ]
Louis, Pierre [1 ]
Selton, Olivier [1 ]
de la Chaise, Arnaud Terrier [1 ]
De Chillou, Christian [1 ]
机构
[1] Nancy Univ Hosp, Dept Cardiol, F-54511 Vandoeuvre Les Nancy, France
关键词
1:1 atrial flutter; Proarrhythmic effect; Anti-arrhythmic drugs; Atrial flutter; Ablation; 1-1; ATRIOVENTRICULAR-CONDUCTION; ANTIARRHYTHMIC-DRUGS; RADIOFREQUENCY ABLATION; FIBRILLATION; TACHYCARDIA; POPULATION; MANAGEMENT; PREDICTORS; AMIODARONE; PATIENT;
D O I
10.1016/j.ijcard.2013.04.047
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Little is known about the epidemiology of 1:1 atrial flutter (AFL). Our objectives were to determine its prevalence and predisposing conditions. Methods:1037 patients aged 16 to 93 years (mean 64 +/- 12) were consecutively referred for AFL ablation. 791 had heart disease (HD). Patients admitted with 1/1 AFL were collected. Patients were followed 3 +/- 3 years. Results:1:1 AFL-related tachycardiomyopathy was found in 85 patients, 59 men (69%) with a mean age of 59 +/- 12 years. The prevalence was 8%. They were compared to 952 patients, 741 men (78%, 0.04), with a mean age of 65 +/- 12 years (0.002) without 1:1 AFL. Factors favoring 1:1 AFL was the absence of HD (35 vs 23%, 0.006), the history of AF (42 vs 30.5%)(0.025) and the use of class I antiarrhythmic drugs (34 vs 13%)(p < 0.0001), while use of amiodarone or beta blockers was less frequent in patients with 1:1 AFL (5, 3.5%) than in patients without 1:1 AFL (25, 15%) (p < 0.0001, 0.03). The failure of ablation (9.4 vs 11%), ablation-related complications (2.3 vs 1.4%), risk of subsequent atrial fibrillation (AF) (20 vs 24%), risk of AFL recurrences (19 vs 13%) and risk of cardiac death (5 vs 6%) were similar in patients with and without 1:1 AFL. Conclusions:The prevalence of 1:1 AFL inpatients admitted for AFL ablation was 8%. These patients were younger, had less frequent HD, had more frequent history of AF and received more frequently class I antiarrhythmic drugs than patients without 1:1 AFL. Their prognosis was similar to patients without 1:1 AFL. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:3287 / 3290
页数:4
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