Quick synthesis of 2-propanol derived fluorescent carbon dots for bioimaging applications

被引:8
作者
Angamuthu, Raja [1 ]
Palanisamy, Priya [1 ]
Vasudevan, Vasanthakumar [1 ]
Nagarajan, Sedhu [1 ]
Rajendran, Ramesh [2 ]
Vairamuthu, Raj [1 ,3 ]
机构
[1] Periyar Univ, Dept Chem, Adv Mat Res Lab, Salem 636011, Tamil Nadu, India
[2] Periyar Univ, Dept Phys, Energy & Funct Mat Lab, Salem 636011, Tamil Nadu, India
[3] Periyar Univ, Ctr Nanosci & Nanotechnol, Salem 636011, Tamil Nadu, India
关键词
Carbon dots; Facile synthesis; Surface morphology; Cytotoxicity; Cell imaging; GRAPHENE QUANTUM DOTS; OXYGEN REDUCTION; NANOPARTICLES; PHOTOLUMINESCENCE; LIGHT; NANOCRYSTALS; ENHANCEMENT; NANODIAMOND; PERFORMANCE; EXTRACTION;
D O I
10.1016/j.optmat.2018.03.002
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Herein, for the first time, we present a one-pot ingenious preparative method for fluorescent carbon dots from 2-propanol (2P-CDs) without external treatments. Structure, morphology, chemical composition and fluorescence properties of the 2P-CDs were examined. These results confirm that the as-synthesized 2P-CDs are amorphous, monodispersed, spherical and the average particle size is 2.5 +/- 0.7 nm. Most importantly, excitation-dependent emission properties were observed, which suggest that these 2P-CDs may be used in multicolor bioimaging applications. When incubated with HeLa cells, the 2P-CDs exhibit low cytotoxicity, and positive biocompatibility. Confocal microscopy image shows the uptake of 2P-CDs by HeLa cells and the application of probable biomarker is demonstrated. (C) 2018 Elsevier B.V. All rights reserved.
引用
收藏
页码:477 / 483
页数:7
相关论文
共 44 条
[1]   Surface functionalized carbogenic quantum dots [J].
Bourlinos, Athanasios B. ;
Stassinopoulos, Andreas ;
Anglos, Demetrios ;
Zboril, Radek ;
Karakassides, Michael ;
Giannelis, Emmanuel P. .
SMALL, 2008, 4 (04) :455-458
[2]   Carbon dots for multiphoton bioimaging [J].
Cao, Li ;
Wang, Xin ;
Meziani, Mohammed J. ;
Lu, Fushen ;
Wang, Haifang ;
Luo, Pengju G. ;
Lin, Yi ;
Harruff, Barbara A. ;
Veca, L. Monica ;
Murray, Davoy ;
Xie, Su-Yuan ;
Sun, Ya-Ping .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (37) :11318-+
[3]   The synergistic role of carbon quantum dots for the improved photocatalytic performance of Bi2MoO6 [J].
Di, Jun ;
Xia, Jiexiang ;
Ji, Mengxia ;
Li, Hongping ;
Xu, Hui ;
Li, Huaming ;
Chen, Rong .
NANOSCALE, 2015, 7 (26) :11433-11443
[4]   Extraction of Electrochemiluminescent Oxidized Carbon Quantum Dots from Activated Carbon [J].
Dong, Yongqiang ;
Zhou, Nana ;
Lin, Xiaomei ;
Lin, Jianpeng ;
Chi, Yuwu ;
Chen, Guonan .
CHEMISTRY OF MATERIALS, 2010, 22 (21) :5895-5899
[5]   Luminescent passive-oxidized silicon quantum dots as biological staining labels and their cytotoxicity effects at high concentration [J].
Fujioka, Kouki ;
Hiruoka, Masaki ;
Sato, Keisuke ;
Manabe, Noriyoshi ;
Miyasaka, Ryosuke ;
Hanada, Sanshiro ;
Hoshino, Akiyoshi ;
Tilley, Richard D. ;
Manome, Yoshinobu ;
Hirakuri, Kenji ;
Yamamoto, Kenji .
NANOTECHNOLOGY, 2008, 19 (41)
[6]   A graphene quantum dot photodynamic therapy agent with high singlet oxygen generation [J].
Ge, Jiechao ;
Lan, Minhuan ;
Zhou, Bingjiang ;
Liu, Weimin ;
Guo, Liang ;
Wang, Hui ;
Jia, Qingyan ;
Niu, Guangle ;
Huang, Xing ;
Zhou, Hangyue ;
Meng, Xiangmin ;
Wang, Pengfei ;
Lee, Chun-Sing ;
Zhang, Wenjun ;
Han, Xiaodong .
NATURE COMMUNICATIONS, 2014, 5
[7]   Graphene Quantum Dots Supported by Graphene Nanoribbons with Ultrahigh Electrocatalytic Performance for Oxygen Reduction [J].
Jin, Huile ;
Huang, Huihui ;
He, Yuhua ;
Feng, Xin ;
Wang, Shun ;
Dai, Liming ;
Wang, Jichang .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2015, 137 (24) :7588-7591
[8]   Formation Mechanism of Carbogenic Nanoparticles with Dual Photoluminescence Emission [J].
Krysmann, Marta J. ;
Kelarakis, Antonios ;
Dallas, Panagiotis ;
Giannelis, Emmanuel P. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (02) :747-750
[9]   Bioimaging of targeting cancers using aptamer-conjugated carbon nanodots [J].
Lee, Chang Hyun ;
Rajendran, Ramesh ;
Jeong, Myoung-Seok ;
Ko, Hae Young ;
Joo, Jin Young ;
Cho, Sujeong ;
Chang, Young Wook ;
Kim, Soonhag .
CHEMICAL COMMUNICATIONS, 2013, 49 (58) :6543-6545
[10]   One-step ultrasonic synthesis of water-soluble carbon nanoparticles with excellent photoluminescent properties [J].
Li, Haitao ;
He, Xiaodie ;
Liu, Yang ;
Huang, Hui ;
Lian, Suoyuan ;
Lee, Shuit-Tong ;
Kang, Zhenhui .
CARBON, 2011, 49 (02) :605-609