Mental Health, Social Influences, and HIV Pre-exposure Prophylaxis (PrEP) Utilization Among Men and Transgender Individuals Screening for HIV Prevention Trials

被引:9
作者
Wood, Sarah M. [1 ,2 ,3 ]
Morales, Knashawn H. [2 ]
Metzger, David [2 ]
Davis, Annet [2 ]
Fiore, Danielle [2 ]
Petsis, Danielle [1 ]
Barnett, Kezia [1 ]
Koenig, Helen C. [2 ]
Dowshen, Nadia [1 ,2 ]
Gross, Robert [2 ]
Frank, Ian [2 ]
机构
[1] Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA
[2] Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA
[3] Childrens Hosp Philadelphia, Roberts Ctr Pediat Res, 11th Floor,Room 11212,2716 South St, Philadelphia, PA 19146 USA
关键词
HIV; Depression; Social networks; Pre-exposure prophylaxis; DEPRESSIVE SYMPTOMS; YOUNG MEN; MULTIDIMENSIONAL SCALE; BISEXUAL MEN; SEXUAL RISK; ADHERENCE; WOMEN; CARE; SUPPORT; GAY;
D O I
10.1007/s10461-020-03004-y
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The effects of mental health comorbidities and social support on the HIV pre-exposure prophylaxis (PrEP) care continuum are unknown. We conducted a cross-sectional study of men and transgender individuals, >= 18 years-old, with >= 2 male or transgender partners, or recent condomless anal intercourse. Surveys assessed demographics, mental health treatment, depressive symptomatology, social support, and PrEP-related social contacts. Logistic regression assessed associations between these factors and PrEP uptake and persistence. Participants (n = 247) were 89% cis-male and 46% African-American. Median age was 27 (IQR:23-33). Thirty-seven percent had ever used PrEP, of whom 18% discontinued use. High depressive symptomology was identified in 11% and 9% were receiving mental health treatment. There were no significant associations between depressive symptoms or mental health treatment on the odds of PrEP uptake or discontinuation. Each additional PrEP contact conferred a greater odds of uptake (aOR:1.24, 95% CI: 1.09-1.42). Network-level targets may produce fruitful interventions to increase PrEP uptake.
引用
收藏
页码:524 / 531
页数:8
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