Genotoxic stresses promote clonal expansion of hematopoietic stem cells expressing mutant p53

被引:24
作者
Chen, S. [1 ]
Gao, R. [2 ,3 ]
Yao, C. [2 ]
Kobayashi, M. [2 ]
Liu, S. Z. [2 ]
Yoder, M. C. [2 ]
Broxmeyer, H. [4 ]
Kapur, R. [2 ]
Boswell, H. S. [5 ]
Mayo, L. D. [1 ,2 ]
Liu, Y. [1 ,2 ]
机构
[1] Indiana Univ Sch Med, Dept Biochem & Mol Biol, Indianapolis, IN 46202 USA
[2] Indiana Univ Sch Med, Herman B Wells Ctr Pediat Res, Dept Pediat, Indianapolis, IN 46202 USA
[3] Shanghai Univ Tradit Chinese Med, Shanghai Municipal Hosp Tradit Chinese Med, Dept Rheumatism, Shanghai, Peoples R China
[4] Indiana Univ Sch Med, Dept Microbiol & Immunol, Indianapolis, IN 46202 USA
[5] Indiana Univ Sch Med, Dept Med, Indianapolis, IN 46202 USA
关键词
ACUTE MYELOID-LEUKEMIA; MUTATIONS; CANCER; GAIN;
D O I
10.1038/leu.2017.325
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:850 / 854
页数:5
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