Poor Decision Making Is Associated with an Increased Risk of Mortality among Community-Dwelling Older Persons without Dementia

被引:36
作者
Boyle, Patricia A. [1 ,2 ]
Wilson, Robert S. [1 ,2 ,3 ]
Yu, Lei [1 ,3 ]
Buchman, Aron S. [1 ,3 ]
Bennett, David A. [1 ,3 ]
机构
[1] Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA
[2] Rush Univ, Med Ctr, Dept Behav Sci, Chicago, IL 60612 USA
[3] Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA
关键词
MILD COGNITIVE IMPAIRMENT; ALZHEIMER-DISEASE; FINANCIAL ABILITIES; CAPACITY; MEMORY; ADULTS; COMPETENCE; DECLINE; AGE;
D O I
10.1159/000342781
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background: Decision making is thought to be an important determinant of health and well-being across the lifespan, but little is known about the association of decision making with mortality. Methods: Participants were 675 older persons without dementia from the Rush Memory and Aging Project, a longitudinal cohort study of aging. Baseline assessments of decision making were used to predict the risk of mortality during up to 4 years of follow-up. Results: The mean score on the decision making measure at baseline was 7.1 (SD = 2.9, range: 0-12), with lower scores indicating poorer decision making. During up to 4 years of follow-up (mean = 1.7 years), 40 (6% of 675) persons died. In a proportional hazards model adjusted for age, sex and education, the risk of mortality increased by about 20% for each additional decision making error (HR = 1.19, 95% CI = 1.07-1.32, p = 0.002). Thus, a person who performed poorly on the measure of decision making (score = 3, 10th percentile) was about 4 times more likely to die compared to a person who performed well (score = 11, 90th percentile). Further, the association of decision making with mortality persisted after adjustment for the level of cognitive function. Conclusion: Poor decision making is associated with an increased risk of mortality in old age even after accounting for cognitive function. Copyright (C) 2013 S. Karger AG, Basel
引用
收藏
页码:247 / 252
页数:6
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