Daddy Issues: Paternal Effects on Phenotype

被引：216

作者：

Rando, Oliver J. ^{[1
]}

机构：

[1] Univ Massachusetts, Sch Med, Dept Biochem & Mol Pharmacol, Worcester, MA 01605 USA

来源：

CELL | 2012年 / 151卷 / 04期

关键词：

TRANSGENERATIONAL EPIGENETIC INHERITANCE; DOUBLE-STRANDED-RNA; CAENORHABDITIS-ELEGANS; MOUSE; TRANSMISSION; ARABIDOPSIS; METHYLATION; MECHANISMS; RESPONSES; DYNAMICS;

D O I：

10.1016/j.cell.2012.10.020

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The once popular and then heretical idea that ancestral environment can affect the phenotype of future generations is coming back into vogue due to advances in the field of epigenetic inheritance. How paternal environmental conditions influence the phenotype of progeny is now a tractable question, and researchers are exploring potential mechanisms underlying such effects.

引用

页码：702 / 708

页数：7

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