TRACKING BLOOD LEAD AND ZINC PROTOPORPHYRIN LEVELS IN ANDEAN ADULTS WORKING IN A LEAD CONTAMINATED ENVIRONMENT

被引：13

作者：

Ortega, Fernando ^{[1
,2
]}

Counter, S. Allen ^{[3
,4
]}

Buchanan, Leo H. ^{[5
,6
]}

Coronel Parra, Angelica Maria ^{[7
]}

Angela Collaguaso, Maria ^{[7
]}

Jacobs, Anthony B. ^{[8
]}

机构：

[1] Colegio Ciencias Salud, Escuela Med, Escuela Salud Publ,Inst Arts & Sci GAIAS, Colegio Artes Liberales & Galapagos, Quito, Ecuador

[2] Univ San Francisco Quito, Quito, Ecuador

[3] Harvard Univ, Sch Med, Biol Labs, Dept Neurol, Cambridge, MA 02138 USA

[4] Massachusetts Gen Hosp, Dept Neurophysiol, Boston, MA 02114 USA

[5] Univ Massachusetts, Sch Med, Eunice Kennedy Shriver Ctr, Dept Pediat, Waltham, MA USA

[6] Harvard Univ, Hlth Serv, Dept Otolaryngol, Cambridge, MA 02138 USA

[7] Subctr Salud, Pujili, Cotopaxi, Ecuador

[8] Harvard Biol Labs, Cambridge, MA USA

来源：

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES | 2013年 / 76卷 / 19期

基金：

美国国家卫生研究院;

关键词：

BREAST-MILK; COMET ASSAY; DNA-DAMAGE; EXPOSURE; WORKERS; CHILDREN; PERFORMANCE;

D O I：

10.1080/15287394.2013.840708

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The purpose of this study was to investigate current blood lead (PbB) and zinc protoporphyrin (ZPP) levels in adults presently living in environmentally Pb-contaminated Andean communities, and to compare the findings with the PbB and ZPP levels of Pb-exposed adult cohorts from the same study area tested between 1996 and 2007. Blood samples from 39 adults were measured for PbB and ZPP concentrations. The current mean PbB level (22.7 g/dl) was significantly lower than the mean (37.9 g/dl) of the initial 1996 cohort. PbB levels for the 1997, 1998, 2003, and 2006 cohorts were also significantly lower than the levels for the 1996 group. Elevated ZPP/heme ratios of 103.3, 128.4, and 134.2 mol/mol were not significantly different for the 2006, 2007, and 2012 groups, indicating chronic Pb exposure. While ZPP levels of Andean Ecuadorian Pb-glazing workers have remained elevated, PbB levels declined. Lead exposure of the workers needs to be continually monitored.

引用

页码：1111 / 1120

页数：10

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