Determination of binding constants by affinity capillary electrophoresis, electrospray ionization mass spectrometry and phase-distribution methods

被引：129

作者：

Chen, Zhi ^{[1
]}

Weber, Stephen G. ^{[1
]}

机构：

[1] Univ Pittsburgh, Dept Chem, Pittsburgh, PA 15260 USA

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2008年 / 27卷 / 09期

关键词：

Affinity capillary electrophoresis; Binding constant; Chemical equilibrium; Electrospray ionization; Intermolecular interaction; Ligand; Mass spectrometry; Phase transfer; Solid-phase microextraction;

D O I：

10.1016/j.trac.2008.06.008

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Many methods for determining intermolecular interactions have been described in the literature in the past several decades. Chief among them are methods based on spectroscopic changes, particularly those based on absorption or nuclear magnetic resonance (NMR) [especially proton NMR (H-1 NMR)]. Recently, there have been put forward several new methods that are particularly adaptable, use very small quantities of material, and that do not place severe requirements on the spectroscopic properties of the binding partners. This review covers new developments in affinity capillary electrophoresis, electrospray ionization mass spectrometry (ESI-MS) and phase-transfer methods. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：738 / 748

页数：11

共 119 条

[1] The effect of ternary complex formation on the partitioning of pyrene and anthracene in aqueous solutions containing sodium dodecyl sulfate and M-gamma-cyclodextrin [J].