Maternal cytoglobin (CYGB) serum levels in normal and preeclamptic pregnancies

被引：1

作者：

Tayyar, Ahter Tanay ^{[1
]}

Tayyar, Ahmet ^{[2
]}

Kozali, Sukran ^{[1
]}

Karakus, Resul ^{[1
]}

Karakus, Seren ^{[1
]}

Yuksel, Ilkbal Temel ^{[2
]}

Dag, Ismail ^{[3
]}

Yildirim, Gonca Yetkin ^{[2
]}

Demirci, Oya ^{[1
]}

机构：

[1] Hlth Sci Univ, Zeynep Kamil Matern & Childrens Training & Res Ho, Dept Obstet & Gynecol, Istanbul, Turkey

[2] Hlth Sci Univ, Kanuni Sultan Suleyman Educ & Res Hosp, Dept Obstet & Gynecol, Istanbul, Turkey

[3] Eyup State Hosp, Dept Clin Biochem, Istanbul, Turkey

来源：

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE | 2019年 / 32卷 / 11期

关键词：

Cytoglobin; early-onset preeclampsia; late-onset preeclampsia; oxidative stress; treatment; HYPERTENSION; NEUROGLOBIN; GLOBIN; WOMEN;

D O I：

10.1080/14767058.2017.1421927

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: To investigate cytoglobin levels in women with preeclampsia and women with uncomplicated pregnancies.Materials and methods: A cross-sectional study including 26 pregnant women complicated with early-onset preeclampsia (EO-PE) and 26 pregnant women complicated with late-onset preeclampsia (LO-PE) were recruited for the study group. Twenty-seven healthy pregnant women selected randomly were included in the control group. The serum CYGB concentrations were measured using an enzyme-linked immunosorbent assay.Results: Gestational age at delivery and mean birth weight were significantly lower in the preeclampsia groups than in the control group and were found to be the lowest in the EO-PE group (p<.001). Serum CYGB levels were significantly higher in the EO-PE and LO-PE groups as compared with the control group (9.99 (6.08) ng/ml (EOPE), 10.04 (7.04) ng/ml (LOPE) versus 2.84 (0.82) ng/ml), (p<.001). However, a significant difference was not found between the EO-PE and LO-PE groups regarding CYGB levels (p=1.000).Conclusions: Serum CYGB levels were significantly higher in patients with EO-PE and LO-PE as compared to healthy pregnant women.

引用

页码：1859 / 1863

页数：5

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