Olfactory Loss in Parkinson's Disease

被引:97
作者
Haehner, Antje [1 ,2 ]
Hummel, Thomas [1 ]
Reichmann, Heinz [2 ]
机构
[1] Tech Univ Dresden, Sch Med, Dept Otorhinolaryngol, D-01307 Dresden, Germany
[2] Tech Univ Dresden, Sch Med, Dept Neurol, D-01307 Dresden, Germany
关键词
ODOR IDENTIFICATION; DE-NOVO; DYSFUNCTION; HYPOSMIA; IMPAIRMENT; BULB; ASSOCIATION; PERFORMANCE; PREDICTORS; SYMPTOMS;
D O I
10.4061/2011/450939
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Impairment of olfaction is a characteristic and early feature of Parkinson's disease. Recent data indicate that >95% of patients with Parkinson's disease present with significant olfactory loss. Deficits in the sense of smell may precede clinical motor symptoms by years and can be used to assess the risk for developing Parkinson's disease in otherwise asymptomatic individuals. This paper summarizes the available information about olfactory function in Parkinson's disease, indicating the advantageous use of olfactory probes in early and differential diagnosis.
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页数:6
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